药物不良反应杂志
藥物不良反應雜誌
약물불량반응잡지
ADVERSE DRUG REACTIONS JOURNAL
2014年
5期
303-304
,共2页
孟鲁司特钠%四肢麻木%震颤%呼吸困难
孟魯司特鈉%四肢痳木%震顫%呼吸睏難
맹로사특납%사지마목%진전%호흡곤난
Montelukast sodium%Numbness of extremities%Tremor%Dyspnea
1例45岁女性患者因慢性支气管炎急性发作，给予左氧氟沙星静脉滴注（0.4 g，1次/d），并给予苏黄止咳胶囊（3粒，3次/d）及孟鲁司特钠（10 mg，1次/d，睡前）口服。患者首次口服孟鲁司特钠10 mg后约30 min，出现四肢麻木震颤、呼吸困难、全身乏力，继而出现恶心、呕吐，持续约2h无缓解。停服孟鲁司特钠，左氧氟沙星和苏黄止咳胶囊继续应用，同时给予相应对症处理。观察至次日下午16：00，患者四肢麻木震颤、呼吸困难症状缓解，未再出现恶心、呕吐。
1例45歲女性患者因慢性支氣管炎急性髮作，給予左氧氟沙星靜脈滴註（0.4 g，1次/d），併給予囌黃止咳膠囊（3粒，3次/d）及孟魯司特鈉（10 mg，1次/d，睡前）口服。患者首次口服孟魯司特鈉10 mg後約30 min，齣現四肢痳木震顫、呼吸睏難、全身乏力，繼而齣現噁心、嘔吐，持續約2h無緩解。停服孟魯司特鈉，左氧氟沙星和囌黃止咳膠囊繼續應用，同時給予相應對癥處理。觀察至次日下午16：00，患者四肢痳木震顫、呼吸睏難癥狀緩解，未再齣現噁心、嘔吐。
1례45세녀성환자인만성지기관염급성발작，급여좌양불사성정맥적주（0.4 g，1차/d），병급여소황지해효낭（3립，3차/d）급맹로사특납（10 mg，1차/d，수전）구복。환자수차구복맹로사특납10 mg후약30 min，출현사지마목진전、호흡곤난、전신핍력，계이출현악심、구토，지속약2h무완해。정복맹로사특납，좌양불사성화소황지해효낭계속응용，동시급여상응대증처리。관찰지차일하오16：00，환자사지마목진전、호흡곤난증상완해，미재출현악심、구토。
A 45-year-old woman received an intravenous injection of levofloxacin( 0. 4 g,once daily),Suhuangzhike(苏黄止咳)capsules(3 capsules,thrice daily)by mouth,and montelukast sodium (10 mg at bedtime,once daily)by mouth for acute attack of chronic bronchitis. About 30 min after the first administration of montelukast sodium,the patient developed numbness of extremities and tremor,dyspnea, and generalized weakness,followed by nausea and vomiting and the symptoms lasted for about 2 hours without alleviating. Montelukast sodium was discontinued,levofloxacin and Suhuangzhike capsules were applied continuously,and symptomatic treatments were given at the same time. The numbness of extremities and tremor and dyspnea relieved,nausea and vomiting did not recur until 16 :00 of the following day.
