CAJ | 학술논문

1例17岁女性患者因感染性心内膜炎静脉滴注头孢美唑钠（2 g，3次/d）和阿米卡星（0.4 g，1次/d）。用药6天血常规检查示白细胞计数23.4×109/L，中性粒细胞0.92，中性粒细胞绝对值21.6×109/L。用药第13天血常规检查示白细胞计数6.6×109/L，中性粒细胞0.70，中性粒细胞绝对值4.6×109/L。第14天停用阿米卡星，继续原剂量静脉滴注头孢美唑钠。用药第28天血常规检查示白细胞计数2.6×109/L，中性粒细胞0.37，中性粒细胞绝对值1.0×109/L。停用头孢美唑钠，更换为万古霉素粉针0.5 g，1次/8 h静脉滴注。更换药物后第7天，血白细胞计数6.1×109/L，中性粒细胞0.60，中性粒细胞绝对值3.7×109/L。
1례17세녀성환자인감염성심내막염정맥적주두포미서납（2 g，3차/d）화아미잡성（0.4 g，1차/d）。용약6천혈상규검사시백세포계수23.4×109/L，중성립세포0.92，중성립세포절대치21.6×109/L。용약제13천혈상규검사시백세포계수6.6×109/L，중성립세포0.70，중성립세포절대치4.6×109/L。제14천정용아미잡성，계속원제량정맥적주두포미서납。용약제28천혈상규검사시백세포계수2.6×109/L，중성립세포0.37，중성립세포절대치1.0×109/L。정용두포미서납，경환위만고매소분침0.5 g，1차/8 h정맥적주。경환약물후제7천，혈백세포계수6.1×109/L，중성립세포0.60，중성립세포절대치3.7×109/L。
A 17-year-old woman with infectious endocarditis received an IV infusion of cefmetazole sodium 2 g three times daily and amikacin 0. 4 g once daily. On day 6 of treatment,blood routine examination revealed the following levels:leucocyte count 23. 4 × 109/L, neutrophile granulocyte 0. 92,neutrophil granulocyte absolute value 21. 6 × 109/L. On day 13 of treatment,blood routine examination revealed the following levels:leucocyte count 6. 6 × 109/L,neutrophile granulocyte 0. 70,neutrophil granulocyte absolute value 4. 6 × 109/L. On day 14,amikacin was withdrawn and IV infusion of cefmetazole sodium was given at the original dose sequentially. On day 28 of treatment,blood routine examination revealed the following values:leucocyte count 2. 6 × 109/L,neutrophile granulocyte 0. 37,neutrophil granulocyte absolute value 1. 0 × 109/L. Cefmetazole sodium was withdrawn and changed to an IV infusion of vancomycin 0. 5 g every 8 hours. Seven days after replacement of drug,blood routine examination revealed the following:leucocyte count 6. 1 × 109/L,neutrophile granulocyte 0. 60,neutrophil granulocyte absolute value 3. 7 × 109/L.