CAJ | 학술논문

目的：探讨儿童淋巴管畸形的诊疗方法及疗效。方法回顾性分析本院近年来采用数字减影血管造影技术（digital subtraction angiography，DSA）瘤内注射平阳霉素治疗的44例淋巴管畸形患儿临床资料，并进行随访。结果44例患儿均在DSA透视下实施平阳霉素瘤内注射1～7次，治愈14例（32％），显效16例（36％），有效13例（30％），无效1例（2％）。随访6个月至2年，疗效满意，病灶区无瘢痕及色素沉着，术后无明显并发症，总有效率达98％。结论 DSA透视下瘤内注射平阳霉素治疗儿童淋巴管畸形定位准确，损伤小，并发症少，疗效显著，不影响外观和功能，无明显不良反应，对于手术难以切除的淋巴管畸形是一种较好的微创治疗方法。
목적：탐토인동림파관기형적진료방법급료효。방법회고성분석본원근년래채용수자감영혈관조영기술（digital subtraction angiography，DSA）류내주사평양매소치료적44례림파관기형환인림상자료，병진행수방。결과44례환인균재DSA투시하실시평양매소류내주사1～7차，치유14례（32％），현효16례（36％），유효13례（30％），무효1례（2％）。수방6개월지2년，료효만의，병조구무반흔급색소침착，술후무명현병발증，총유효솔체98％。결론 DSA투시하류내주사평양매소치료인동림파관기형정위준학，손상소，병발증소，료효현저，불영향외관화공능，무명현불량반응，대우수술난이절제적림파관기형시일충교호적미창치료방법。
Objetive To investigate the efficacy and adverse reactions of minimally invasive intervention in treating lymphatic malformations in children. Methods Retrospective analysis was given to the clinical data from 44 cases of lymphatic malformations which was treated with intratumoral injection of bleomycin under DSA (digital subtraction angiography)and fluoroscopy,and followed-up. Results 44 cases of lymphatic malfor-mations of children were treated 1 to 7 intratumoral injection of bleomycin that carried out under DSA and fluo-roscopy.Followe-up ranged from 6 months to 2 years,1 4 cases (32%)were cured,1 6 cases (36%)were markedly effective,1 3 cases (30%)were effective and 1 case (2%)is ineffective.The total effective rates was 98%and no scarring,pigmentation and significant postoperative complications. Conclusion Intratumoral injection of bleomycin carried out under DSA and fluoroscopy is an effective and safe method of treating lym-phatic malformations and have the advantages in cluding positioning accuracy,less damage,fewer complica-tions,no affect on appearance,no damage in function and no significant adverse reaction.Especially in trea-ting the complicate lymphatic malformations which is hard to remove by traditional surgery.