中国性科学
中國性科學
중국성과학
THE CHINESE JOURNAL OF HUMAN SEXUALITY
2014年
10期
76-78
,共3页
张阳阳%徐阳%张蕾%薛晴%尚!%郐艳荣%王晟%鞠慧岩%陈菲%廖秦平
張暘暘%徐暘%張蕾%薛晴%尚!%鄶豔榮%王晟%鞠慧巖%陳菲%廖秦平
장양양%서양%장뢰%설청%상!%회염영%왕성%국혜암%진비%료진평
卵巢低反应%控制性超促排卵%辅助生殖技术%妊娠结局
卵巢低反應%控製性超促排卵%輔助生殖技術%妊娠結跼
란소저반응%공제성초촉배란%보조생식기술%임신결국
Poor ovarian response%Controlled ovarian hyperstimulation%Assisted reproductive technology%Pregnancy result
目的：研究控制性超促排卵下卵巢低反应的预测指标及妊娠结局情况。方法：选择拟行IVF/ICSI助孕治疗的152名不孕症女性，根据卵巢反应性分为两组：低反应组（获卵数＜4个）、非低反应组（获卵数≥4个）。收集不孕症女性的相关临床资料进行分析。结果：卵巢低反应的发生率为18.42％（28/152）。两组中年龄、基础FSH值、FSH/LH值、AFC 有显著性差异。多因素Logistic 回归分析显示：年龄和AFC进入回归模型，年龄与卵巢反应性呈负相关，AFC与卵巢反应性成正相关。周期取消率为19.74％（30/152），卵巢低反应组（35.71％，10/28）明显高于非低反应组（16.13％，20/124）。移植周期临床妊娠率为51.64％（63/122），卵巢低反应组（22.22％，4/18）明显低于非低反应组（56.73％，59/104）。结论：年龄和AFC可用于卵巢低反应的预测。卵巢低反应可导致周期取消率升高、临床妊娠率降低。
目的：研究控製性超促排卵下卵巢低反應的預測指標及妊娠結跼情況。方法：選擇擬行IVF/ICSI助孕治療的152名不孕癥女性，根據卵巢反應性分為兩組：低反應組（穫卵數＜4箇）、非低反應組（穫卵數≥4箇）。收集不孕癥女性的相關臨床資料進行分析。結果：卵巢低反應的髮生率為18.42％（28/152）。兩組中年齡、基礎FSH值、FSH/LH值、AFC 有顯著性差異。多因素Logistic 迴歸分析顯示：年齡和AFC進入迴歸模型，年齡與卵巢反應性呈負相關，AFC與卵巢反應性成正相關。週期取消率為19.74％（30/152），卵巢低反應組（35.71％，10/28）明顯高于非低反應組（16.13％，20/124）。移植週期臨床妊娠率為51.64％（63/122），卵巢低反應組（22.22％，4/18）明顯低于非低反應組（56.73％，59/104）。結論：年齡和AFC可用于卵巢低反應的預測。卵巢低反應可導緻週期取消率升高、臨床妊娠率降低。
목적：연구공제성초촉배란하란소저반응적예측지표급임신결국정황。방법：선택의행IVF/ICSI조잉치료적152명불잉증녀성，근거란소반응성분위량조：저반응조（획란수＜4개）、비저반응조（획란수≥4개）。수집불잉증녀성적상관림상자료진행분석。결과：란소저반응적발생솔위18.42％（28/152）。량조중년령、기출FSH치、FSH/LH치、AFC 유현저성차이。다인소Logistic 회귀분석현시：년령화AFC진입회귀모형，년령여란소반응성정부상관，AFC여란소반응성성정상관。주기취소솔위19.74％（30/152），란소저반응조（35.71％，10/28）명현고우비저반응조（16.13％，20/124）。이식주기림상임신솔위51.64％（63/122），란소저반응조（22.22％，4/18）명현저우비저반응조（56.73％，59/104）。결론：년령화AFC가용우란소저반응적예측。란소저반응가도치주기취소솔승고、림상임신솔강저。
Objectives:To study the predictive indicators and pregnancy outcome of poor ovarian response in controlled ovarian hyperstimulation.Methods:A total of 152 infertile women undergoing IVF/ICSI were included in this study and divided into 2 groups according to the number of retrieved oocytes:poor ovarian responders (<4 oocytes);non-poor ovarian responders (≥4 oocytes).Clinical data,including age,duration of infertility,basal follicle stimulating hormone (FSH)level,antral follicle count (AFC),total dosages of gonadotropins (Gn),total number of retrieved oocytes,and clinical pregnancy outcome were obtained.Results:The incidence of poor ovarian response was 18.42% (28/152).There was significant difference in age,basal FSH,FSH/LH,AFC between poor and non-poor ovarian response.Multi-variate Logistic regression analysis showed a negative correlation be-tween age and ovarian response,and a positive correlation between AFC and ovarian response.In this study,the cy-cle cancellation rate in poor ovarian response (35.71%,10/28)was higher than that of non -poor response (16.13%,20/124).The clinical pregnancy rate in poor ovarian response (22.22%,4/18)was lower than that of non-poor response (56.73%,59/104).Conclusions:Age and AFC can be used as predictive indicators of poor o-varian response.Poor ovarian response may result in higher cycle cancellation rate and lower clinical pregnancy rate.
