CAJ | 학술논문

目的：探讨坤泰胶囊对女性II型糖尿病患者性功能障碍（FSD）的治疗效果。方法：选取44例FSD患者，随机分为对照组和观察组，各22例。观察组给予坤泰胶囊口服治疗，对照组给予西地那非治疗，比较两组患者治疗前后睾酮（T）和雌激素（E2）的水平，并用女性性功能量表（FSFI）测量两组患者治疗前后的性功能变化。结果：观察组治疗后的T和E2水平较治疗前明显升高（P＜0.05），对照组治疗前后无明显变化（P＞0.05）；观察组较治疗前性功能障碍得到了改善，在性欲、性唤起、性高潮、满意度维度以及总体满意度均明显优于治疗前与对照组（P＜0.05），对照组仅在阴道润滑度及疼痛维度较治疗前有所改善（P＜0.05）。结论：坤泰胶囊能有效地改善女性II型糖尿病患者性功能障碍，其机制可能与提高T水平以及E2水平有关。
목적：탐토곤태효낭대녀성II형당뇨병환자성공능장애（FSD）적치료효과。방법：선취44례FSD환자，수궤분위대조조화관찰조，각22례。관찰조급여곤태효낭구복치료，대조조급여서지나비치료，비교량조환자치료전후고동（T）화자격소（E2）적수평，병용녀성성공능량표（FSFI）측량량조환자치료전후적성공능변화。결과：관찰조치료후적T화E2수평교치료전명현승고（P＜0.05），대조조치료전후무명현변화（P＞0.05）；관찰조교치료전성공능장애득도료개선，재성욕、성환기、성고조、만의도유도이급총체만의도균명현우우치료전여대조조（P＜0.05），대조조부재음도윤활도급동통유도교치료전유소개선（P＜0.05）。결론：곤태효낭능유효지개선녀성II형당뇨병환자성공능장애，기궤제가능여제고T수평이급E2수평유관。
Objectives:To evaluate the clinical effects of Kuntai capsule for female sexual dysfunction with type II diabetes (FSD).Methods:44 patients with FSD were randomly divided into control group and observation group,with 22 cases in each group.The patients in observation group were given Kuntai capsule orally,while pa-tients in the control group were given Sildenafil citrate.The levels of testosterone (T)and estradiol (E2)were com-pared before and after treatment in both groups,and sexual function were measured using the female sexual function index (FSFI).Results:The levels of T and E2 in observation group after treatment were significantly elevated com-pared with those before treatment (P<0.05 ),while there were no significant changes in the control group (P>0.05 );sexual dysfunction of patients in the observation group was been improved than those before treatment and in control group,which inclued sexual desire,arousal,orgasm,satisfaction and overall satisfaction (P<0.05 ),vagi-nal lubrication and pain dimension were been improved in the control group only than before treatment(P<0.05 ). Conclusion:Kuntai capsule can effectively improve sexual dysfunction of female patients with type II diabetes,and its mechanism may be related to the increased level of T and E2.