CAJ | 학술논문

目的：探讨男性抑郁症患者药物治疗前后性功能变化情况，以更好的掌握和治疗该类疾病，提高抑郁症患者治疗后性功能。方法：选取2010年4月至2013年4月90例抑郁症患者为研究对象，比较治疗前后在性功能指标孕酮（PROG）、雌二醇（E2）、睾酮（T）、黄体生成素（LH）、促卵泡激素（FSH）、催乳素（PRL）的变化情况。结果：治疗前后在HAMD-17、BSDSRS、IIEF、CISFPE和PROG、E2、T、LH、FSH、PRL比较差异有统计学意义（P＜0．05）。结论：男性抑郁症合并性功能障碍发生率高，多数药物在缓解抑郁同时不能改善性功能状况，且有加重趋势，临床上要选择对性功能影响较低的抗抑郁症药物。
목적：탐토남성억욱증환자약물치료전후성공능변화정황，이경호적장악화치료해류질병，제고억욱증환자치료후성공능。방법：선취2010년4월지2013년4월90례억욱증환자위연구대상，비교치료전후재성공능지표잉동（PROG）、자이순（E2）、고동（T）、황체생성소（LH）、촉란포격소（FSH）、최유소（PRL）적변화정황。결과：치료전후재HAMD-17、BSDSRS、IIEF、CISFPE화PROG、E2、T、LH、FSH、PRL비교차이유통계학의의（P＜0．05）。결론：남성억욱증합병성공능장애발생솔고，다수약물재완해억욱동시불능개선성공능상황，차유가중추세，림상상요선택대성공능영향교저적항억욱증약물。
Objectives:To investigate changes in the sexual function of male patients with depression before and after drug treatment in order to better understand and treat the disease,and improve the sexual function of such patients after treatment.Methods:90 patients with depression from April 2010 to April 2013 were selected for the study,and the sexual function indexes including levels of progesterone (PROG),estradiol (E2 ),testosterone (T),luteinizing hormone (changes in LH),follicle-stimulating hormone (FSH)and prolactin (PRL)before and after treatment were compared.Results:Changes in the HAMD-17,BSDSRS,IIEF,CISFPE and PROG,E2,T, LH,FSH and PRL before and after treatment was of statistically significant differences (P<0.05 ).Conclusion:Male patients with depression are of high incidence of sexual dysfunction,while most drugs in relieving depression cannot improve sexual function;therefore,antidepressant drugs with a smaller impact on sexual function should be chosen in clinical practice.