CAJ | 학술논문

目的：探讨促肾上腺皮质激素(ACTH)联合丙戊酸钠治疗婴儿痉挛的疗效及护理方法。方法选取2010年8月至2013年8月在我院进行治疗的婴儿痉挛患者80例作为研究对象，56例给予ACTH治疗的基础上口服丙戊酸钠作为观察组，24例仅给予ACTH作为对照组。两组均密切观察患儿体征变化，给予及时合理的综合护理。比较两组的临床疗效。结果观察组在痉挛发作疗效以及脑电图疗效均显著优于对照组，差异均有统计学意义(P<0.05)。结论对婴儿痉挛患者进行ACTH联合丙戊酸钠治疗及有效的护理，可以显著提高临床上的总有效率，效果明显优于其单独药，值得临床推广。
목적：탐토촉신상선피질격소(ACTH)연합병무산납치료영인경련적료효급호리방법。방법선취2010년8월지2013년8월재아원진행치료적영인경련환자80례작위연구대상，56례급여ACTH치료적기출상구복병무산납작위관찰조，24례부급여ACTH작위대조조。량조균밀절관찰환인체정변화，급여급시합리적종합호리。비교량조적림상료효。결과관찰조재경련발작료효이급뇌전도료효균현저우우대조조，차이균유통계학의의(P<0.05)。결론대영인경련환자진행ACTH연합병무산납치료급유효적호리，가이현저제고림상상적총유효솔，효과명현우우기단독약，치득림상추엄。
Objective To explore the effect and nursing methods of adrenocorticotrophic hormone (ACTH) combined with sodium valproate for the treatment of infantile spasm. Methods 80 cases of infantile spasm in our hospital from August 2010 to August 2013 were selected as the research objects, in which, 56 cases treated with ACTH combined with sodium valproate were set as the observation group, and 24 cases treated with ACTH alone were set as the control group. Both groups were given comprehensive nursing. The clinical effects of two groups were analyzed and compared. Results The curative effects of convulsive seizure and electroencephalogram of observation group were significantly better than those of control group (P <0.05). Conclusions For infants with spasm, the therapy of ACTH and sodium valproate combined with effective nursing can significantly improve the cure rate.