CAJ | 학술논문

目的：探讨妈富隆联合二甲双胍治疗多囊卵巢综合征的临床疗效。方法选取我院收治的102例多囊卵巢综合征患者，随机均分为对照组(妈富隆治疗)和观察组(妈富隆联合二甲双胍治疗)各51例，比较两组治疗前后临床症状和血清检验指标的差异。结果治疗3个周期后，观察组月经稀少、面部痤疮、多毛等发生率均显著低于对照组(P<0.05)，观察组黄体生成素(LH)、睾酮(T)、黄体生成素/促性腺激素(LH/FSH)、空腹胰岛素(FINS)和空腹血糖(FG)均少于对照组，两组比较差异具有统计学意义(P<0.05)。结论妈富隆联合二甲双胍治疗多囊卵巢综合征疗效确切，可有效改善患者的临床症状和内分泌状况。
목적：탐토마부륭연합이갑쌍고치료다낭란소종합정적림상료효。방법선취아원수치적102례다낭란소종합정환자，수궤균분위대조조(마부륭치료)화관찰조(마부륭연합이갑쌍고치료)각51례，비교량조치료전후림상증상화혈청검험지표적차이。결과치료3개주기후，관찰조월경희소、면부좌창、다모등발생솔균현저저우대조조(P<0.05)，관찰조황체생성소(LH)、고동(T)、황체생성소/촉성선격소(LH/FSH)、공복이도소(FINS)화공복혈당(FG)균소우대조조，량조비교차이구유통계학의의(P<0.05)。결론마부륭연합이갑쌍고치료다낭란소종합정료효학절，가유효개선환자적림상증상화내분비상황。
Objective To investigate the clinical efficacy of marvelon combined with metformin in the treatment of polycystic ovary syndrome. Methods 102 cases of patients with polycystic ovary syndrome treated in our hospital were selected and randomly divided into control group (treated with marvelon) and observation group (treated with marvelon combined with metformin), with 51 cases in each group. The clinical symptoms and serum test indicators before and after the treatment of two groups were compared. Results After three cycles treatment, the rare menstruation, acne and hirsutism rate of the observation group were significantly lower than those of the control group (P<0.05), the luteinizing hormone (LH), testosterone (T), luteinizing hormone/gonadotropin (LH/FSH), fasting insulin (FINS) and fasting blood-glucose (FG) of the observation group were significantly lower than those of the control group, with significant difference (P<0.05). Conclusions The combination of marvelon and metformin in the treatment of polycystic ovary syndrome has curative effect, which can effectively improve the patients' clinical symptoms and endocrine situation.