CAJ | 학술논문

目的：探讨红细胞血型不规则抗体的分布规律及其临床意义。方法应用微柱凝胶抗球蛋白检测技术对6352例患者进行不规则抗体筛查、鉴定。结果在6352例患者中检出红细胞同种不规则抗体阳性者62例（男27例，女35例），阳性率0．97％。有输血史和（或）妊娠史者54例，其中Rh血型系统不规则抗体43例（含抗-E抗体34例），MNSS系统7例，Lewis系统2例，Kidd系统2例，P系统2例，Diego系统1例，无特异性5例。Rh血型系统不规则抗体阳性患者均有输血史和（或）妊娠史。结论不规则抗体阳性患者中女性占多数，大多曾经有输血史和（或）妊娠史，以Rh血型系统抗体最为常见。
목적：탐토홍세포혈형불규칙항체적분포규률급기림상의의。방법응용미주응효항구단백검측기술대6352례환자진행불규칙항체사사、감정。결과재6352례환자중검출홍세포동충불규칙항체양성자62례（남27례，녀35례），양성솔0．97％。유수혈사화（혹）임신사자54례，기중Rh혈형계통불규칙항체43례（함항-E항체34례），MNSS계통7례，Lewis계통2례，Kidd계통2례，P계통2례，Diego계통1례，무특이성5례。Rh혈형계통불규칙항체양성환자균유수혈사화（혹）임신사。결론불규칙항체양성환자중녀성점다수，대다증경유수혈사화（혹）임신사，이Rh혈형계통항체최위상견。
Objective To discuss the distribution of irregular antibodies of red blood cells and its clinical significance .Methods Micro-column gel anti-globulin technique was used to screen and identify the irregular antibodies in 6 352 patients .Results In 6 352 patients ,there were 62 cases(27 males ,35 females)having positive results in irregular antibody detection ,and the positive rate was 0 .97% .There were 54 cases having transfusion history and/or pregnancy history ,including 43 cases of irregular antibodies of Rh system(containing 34 cases of anti-E antibody) ,7 cases of MNSS system ,2 cases of Lewis system ,2 cases of Kidd system ,2 cases of P system ,1 cases of Diego system ,and 5 cases with non-specificity .All of the patients whose irregular antibodies of Rh blood group system were positive had transfusion history and/or pregnancy history .Conclusion Most of the patients with irregular anti-body positive are females ,who mostly have transfusion history and/or pregnancy history ,and the irregular antibodies of Rh system are the most common .