影像诊断与介入放射学
影像診斷與介入放射學
영상진단여개입방사학
JOURNAL OF DIAGNOSTIC IMAGING AND INTERVENTIONAL RADIOLOGY
2014年
5期
371-375
,共5页
廖森成%王君龙%张玉勤%林育成%何有程
廖森成%王君龍%張玉勤%林育成%何有程
료삼성%왕군룡%장옥근%림육성%하유정
无精子症%超声检查%抑制素B
無精子癥%超聲檢查%抑製素B
무정자증%초성검사%억제소B
Azoospermia%Ultrasonography%Inhibin B
目的 评价经阴囊及直肠超声联合血清抑制素B（INHB）检测在鉴别梗阻性无精子症（OA）和非梗阻性无精子症（NOA）中的应用价值。方法 选择无精子症患者100 例，经阴囊超声检查其睾丸及近段精道，经直肠超声检查其远段精道，并检测其血清INHB 水平，以睾丸活检为标准分为OA 组和NOA 组，选择同期的30 例精液检查正常者为对照组，分析比较三组病例的精道超声表现、睾丸体积及血清INHB 水平的差异。结果 本研究检出的精道异常主要包括附睾炎症及畸形，输精管扩张及缺如，精囊炎症、缺如及萎缩，射精管囊肿等；OA 组的精道异常超声表现明显多于NOA 组（P<0.01) ；OA 组患者睾丸体积中位数为13.1 ml，NOA 组患者睾丸体积中位数为7.2 ml，OA 组患者睾丸体积明显大于NOA 组（P<0.05）；OA 组、NOA 组、对照组的血清INHB 浓度分别为（131.2±26.1）pg/ml、（37.5±21.5）pg/ml、（120.7±31.4）pg/ml，OA 组和对照组的血清INHB 水平之间无明显差异（P>0.05），而NOA 组的血清INHB 水平明显低于OA 组和对照组（P<0.01）。结论 经阴囊及直肠超声检查联合血清INHB 检测，能够对无精子症进行比较准确的分型诊断。
目的 評價經陰囊及直腸超聲聯閤血清抑製素B（INHB）檢測在鑒彆梗阻性無精子癥（OA）和非梗阻性無精子癥（NOA）中的應用價值。方法 選擇無精子癥患者100 例，經陰囊超聲檢查其睪汍及近段精道，經直腸超聲檢查其遠段精道，併檢測其血清INHB 水平，以睪汍活檢為標準分為OA 組和NOA 組，選擇同期的30 例精液檢查正常者為對照組，分析比較三組病例的精道超聲錶現、睪汍體積及血清INHB 水平的差異。結果 本研究檢齣的精道異常主要包括附睪炎癥及畸形，輸精管擴張及缺如，精囊炎癥、缺如及萎縮，射精管囊腫等；OA 組的精道異常超聲錶現明顯多于NOA 組（P<0.01) ；OA 組患者睪汍體積中位數為13.1 ml，NOA 組患者睪汍體積中位數為7.2 ml，OA 組患者睪汍體積明顯大于NOA 組（P<0.05）；OA 組、NOA 組、對照組的血清INHB 濃度分彆為（131.2±26.1）pg/ml、（37.5±21.5）pg/ml、（120.7±31.4）pg/ml，OA 組和對照組的血清INHB 水平之間無明顯差異（P>0.05），而NOA 組的血清INHB 水平明顯低于OA 組和對照組（P<0.01）。結論 經陰囊及直腸超聲檢查聯閤血清INHB 檢測，能夠對無精子癥進行比較準確的分型診斷。
목적 평개경음낭급직장초성연합혈청억제소B（INHB）검측재감별경조성무정자증（OA）화비경조성무정자증（NOA）중적응용개치。방법 선택무정자증환자100 례，경음낭초성검사기고환급근단정도，경직장초성검사기원단정도，병검측기혈청INHB 수평，이고환활검위표준분위OA 조화NOA 조，선택동기적30 례정액검사정상자위대조조，분석비교삼조병례적정도초성표현、고환체적급혈청INHB 수평적차이。결과 본연구검출적정도이상주요포괄부고염증급기형，수정관확장급결여，정낭염증、결여급위축，사정관낭종등；OA 조적정도이상초성표현명현다우NOA 조（P<0.01) ；OA 조환자고환체적중위수위13.1 ml，NOA 조환자고환체적중위수위7.2 ml，OA 조환자고환체적명현대우NOA 조（P<0.05）；OA 조、NOA 조、대조조적혈청INHB 농도분별위（131.2±26.1）pg/ml、（37.5±21.5）pg/ml、（120.7±31.4）pg/ml，OA 조화대조조적혈청INHB 수평지간무명현차이（P>0.05），이NOA 조적혈청INHB 수평명현저우OA 조화대조조（P<0.01）。결론 경음낭급직장초성검사연합혈청INHB 검측，능구대무정자증진행비교준학적분형진단。
ObjectiveTo assess the value of scrotal and transrectal ultrasonography(US)together with detection of serum INHB in the classification of azoospermia.Methods 100 patients with azoospermia were evaluated by scrotal and transrectal US and the levels of serum INHB were measured. Patients were classified as obstructive azoospermia(OA)or non-obstructive azoospermia(NOA)according to the results of testicular biopsy. 30 volunteers with normal semen were enrolled as control. The US appearance, testicular volume and level of serum INHB among the three groups were compared.Results US showed epididymal malformation or inflammation, dilatation or absence of the vas deferens, inflammation, atrophy or absence of the seminal vesicle, ejaculatory duct cyst. Abnormalities of the vas deference were more common in OA than that in NOA(P<0.01). The testicular volume in OA was larger than that in NOA(P<0.05). There was no significant difference (P>0.05) in the level of serum INHB between OA(131.2±26.1pg/ml) and control group(120.7±31.4pg/ml) whereas serum INHB was significantly lower(P<0.05) in patients with NOA(37.5±21.5 pg/ml) than that in OA and control group.Conclusion Scrotal and transrectal US together with detection of serum INHB can accurately classify azoospermia.
