国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2013年
7期
548-550
,共3页
睡眠呼吸暂停综合征%慢性间断性缺氧%心血管疾病%动脉粥样硬化
睡眠呼吸暫停綜閤徵%慢性間斷性缺氧%心血管疾病%動脈粥樣硬化
수면호흡잠정종합정%만성간단성결양%심혈관질병%동맥죽양경화
Sleep apnea syndrome%Chronic intermittent hypoxia%Cardiovascular diseases%Atherosclerosis
睡眠呼吸暂停综合征是临床上常见的睡眠呼吸疾病.近几年的研究证实睡眠呼吸暂停综合征是心血管疾病的独立危险因素.阻塞型睡眠呼吸暂停综合征的患者在睡眠时由于上呼吸道的阻塞或者部分阻塞而导致机体长期反复的慢性间断性缺氧,而慢性间断性缺氧是阻塞型睡眠呼吸暂停综合征患者发生心血管疾病的主要原因.内皮机能障碍、氧化应激、炎症激活、血脂障碍、凝血障碍、代谢障碍等因素相互作用导致动脉粥样硬化形成从而引起各种心血管疾病.
睡眠呼吸暫停綜閤徵是臨床上常見的睡眠呼吸疾病.近幾年的研究證實睡眠呼吸暫停綜閤徵是心血管疾病的獨立危險因素.阻塞型睡眠呼吸暫停綜閤徵的患者在睡眠時由于上呼吸道的阻塞或者部分阻塞而導緻機體長期反複的慢性間斷性缺氧,而慢性間斷性缺氧是阻塞型睡眠呼吸暫停綜閤徵患者髮生心血管疾病的主要原因.內皮機能障礙、氧化應激、炎癥激活、血脂障礙、凝血障礙、代謝障礙等因素相互作用導緻動脈粥樣硬化形成從而引起各種心血管疾病.
수면호흡잠정종합정시림상상상견적수면호흡질병.근궤년적연구증실수면호흡잠정종합정시심혈관질병적독립위험인소.조새형수면호흡잠정종합정적환자재수면시유우상호흡도적조새혹자부분조새이도치궤체장기반복적만성간단성결양,이만성간단성결양시조새형수면호흡잠정종합정환자발생심혈관질병적주요원인.내피궤능장애、양화응격、염증격활、혈지장애、응혈장애、대사장애등인소상호작용도치동맥죽양경화형성종이인기각충심혈관질병.
Sleep apnea syndrome is a common clinical sleep respiratory diseases.In recent years,sleep apnea syndrome is confirmed as an independent risk factor for cardiovascular diseases.Due to obstruction or partial obstruction of the upper respiratory tract,patients with obstructive sleep apnea syndrome will happen to the body long-term repeated chronic intermittent hypoxia during sleep.And chronic intermittent hypoxia is the main factor of obstructive sleep apnea syndrome in patients with cardiovascular diseases.Endothelial dysfunction,oxidative stress,inflammatory activation,lipid disorders,coagulation disorders,metabolic disorders,such as the interplay of factors leading to atherosclerosis formation,causing a variety of cardiovascular diseases.
