中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2014年
22期
3448-3449,3450
,共3页
鲍曼不动杆菌%抗菌药物%耐药%多重耐药%临床分布
鮑曼不動桿菌%抗菌藥物%耐藥%多重耐藥%臨床分佈
포만불동간균%항균약물%내약%다중내약%림상분포
Acinetobacter baumannii%anti-bacterial agents%Drug resistance%multi-drug resistance
目的:分析医院感染多重耐药鲍曼不动杆菌临床特征及耐药情况,为临床合理使用抗菌药物提供依据。方法分离的358株鲍曼不动杆菌采用法国生物梅里埃公司ATB自动细菌鉴定分析系统进行细菌鉴定,K-B纸片扩散法进行药敏试验,对所得数据用WHONET5.4软件进行分析。结果临床分离出鲍曼不动杆菌358株,91.62%分离自痰与咽拭子的标本,52.23%来自重症监护病房( ICU);多重耐药鲍曼不动杆菌217株占总数的60.61%。多重耐药鲍曼不动杆菌对多黏菌素B耐药率最低(0.0%),其次为米诺环素(5.1%)、头孢哌酮/舒巴坦(9.8%)、奈替米星(21.1%)和美洛培南(41.5%)。结论 ICU病区的多重耐药鲍曼不动杆菌的比例明显高于其他病区,应根据药敏结果合理使用抗菌药物,减少和控制医院感染的发生。
目的:分析醫院感染多重耐藥鮑曼不動桿菌臨床特徵及耐藥情況,為臨床閤理使用抗菌藥物提供依據。方法分離的358株鮑曼不動桿菌採用法國生物梅裏埃公司ATB自動細菌鑒定分析繫統進行細菌鑒定,K-B紙片擴散法進行藥敏試驗,對所得數據用WHONET5.4軟件進行分析。結果臨床分離齣鮑曼不動桿菌358株,91.62%分離自痰與嚥拭子的標本,52.23%來自重癥鑑護病房( ICU);多重耐藥鮑曼不動桿菌217株佔總數的60.61%。多重耐藥鮑曼不動桿菌對多黏菌素B耐藥率最低(0.0%),其次為米諾環素(5.1%)、頭孢哌酮/舒巴坦(9.8%)、奈替米星(21.1%)和美洛培南(41.5%)。結論 ICU病區的多重耐藥鮑曼不動桿菌的比例明顯高于其他病區,應根據藥敏結果閤理使用抗菌藥物,減少和控製醫院感染的髮生。
목적:분석의원감염다중내약포만불동간균림상특정급내약정황,위림상합리사용항균약물제공의거。방법분리적358주포만불동간균채용법국생물매리애공사ATB자동세균감정분석계통진행세균감정,K-B지편확산법진행약민시험,대소득수거용WHONET5.4연건진행분석。결과림상분리출포만불동간균358주,91.62%분리자담여인식자적표본,52.23%래자중증감호병방( ICU);다중내약포만불동간균217주점총수적60.61%。다중내약포만불동간균대다점균소B내약솔최저(0.0%),기차위미낙배소(5.1%)、두포고동/서파탄(9.8%)、내체미성(21.1%)화미락배남(41.5%)。결론 ICU병구적다중내약포만불동간균적비례명현고우기타병구,응근거약민결과합리사용항균약물,감소화공제의원감염적발생。
Objective To investigate the clinical feature of Acinetobacter baumannii and to provide the basis for clinical rational use of anti-microbial agents.Methods ATB system was used to identify Acinetobacter baumanii, and antimicrobial resistance was determined by Kirby-Bauer method.The results were analyzed by Whonet 5.4 soft-ware.Results A total of the 358 strains Acinetobacter baumannii were isolated,91.62% were from sputum and throat swab.The main departments was ICU(52.23%);In 358 strains Acinetobacter baumannii,217 strains were multi-drug resistant strains(60.61%).The drug resistance to polymyxin B was the lowest 0% followed by minocy-cline 19.8% and cefoperazone/sulbactam 9.8%, the next was netilmicin 21.1% and meropenem 41.5%. Conclusion Acinetobacter baumannii shows multi-drug resistance, especially in ICU.Anti-microbial agents should be the rational use according to the results of drug susceptibility in order to reduce and control the incidence of noso-comial infections.