CAJ | 학술논문

目的：探讨胃癌患者手术前后血清中CEA、CA125、CA242、CA72-4、CA19-9值的变化，以评估手术疗效中的应用价值。方法：入组胃癌患者40例，检测患者手术前、后血清中CEA、CA125、CA242、CA72-4、CA19-9的高低，进行同一患者手术前后结果对照。结果：胃癌根治术后患者血清CEA、CA125、CA242、CA72-4、CA19-9值明显低于手术前(P<0.05)，而仅行姑息性手术的患者血清CEA、CA125、CA242、CA72-4、CA19-9值与术前相比差异无统计学意义(P>0.05)。结论：胃癌患者血清CEA、CA125、CA242、CA72-4、CA19-9存在高水平表达，可用于胃癌手术疗效及预后情况的评估。
목적：탐토위암환자수술전후혈청중CEA、CA125、CA242、CA72-4、CA19-9치적변화，이평고수술료효중적응용개치。방법：입조위암환자40례，검측환자수술전、후혈청중CEA、CA125、CA242、CA72-4、CA19-9적고저，진행동일환자수술전후결과대조。결과：위암근치술후환자혈청CEA、CA125、CA242、CA72-4、CA19-9치명현저우수술전(P<0.05)，이부행고식성수술적환자혈청CEA、CA125、CA242、CA72-4、CA19-9치여술전상비차이무통계학의의(P>0.05)。결론：위암환자혈청CEA、CA125、CA242、CA72-4、CA19-9존재고수평표체，가용우위암수술료효급예후정황적평고。
Objective:To investigate the serum levels of CEA,CA125,CA242,CA72-4,CA19-9 of patients with gastric cancer before and after operation and their significance in evaluate operation effect.Method:Detecting the serum CEA,CA125,CA242,CA72-4,CA19-9 levels in the 40 cases of gastric cancer before and after operation,and making statistic analysis of them.Result:The serum CEA,CA125,CA242,CA72-4, CA19-9 levels in the patients with gastric cancer after radical operation were lower than those before operation(P<0.05).But the variation wasn’t observed after palliative operation(P>0.05).Conclusion:The serum levels of CEA,CA125,CA242,CA72-4,CA19-9 are high of patients with gastric cancer, their detection can be used to evaluate the efficacy of operation for gastric cancer.