当代医学
噹代醫學
당대의학
CHINA CONTEMPORARY MEDICINE
2014年
31期
84-85
,共2页
糖尿病%肺部感染%病原菌%药敏试验
糖尿病%肺部感染%病原菌%藥敏試驗
당뇨병%폐부감염%병원균%약민시험
Diabetes%Pulmonary infection%Pathogens%Drug sensitivity test
目的：探讨老年糖尿病患者合并肺部感染的病原菌分布特点和药敏试验情况，以便为临床用药提供依据。方法选取2005年8月～2010年12月武警湖南总队医院收治的老年糖尿病合并肺部感染患者76例的痰标本，培养、分离病原菌。结果76例患者检出53株病原菌，其中革兰阴性菌占37.74%，多为大肠埃希菌、肺炎克雷伯菌杆菌，对亚胺培南、喹诺酮类抗生素敏感；革兰阳性菌占30.19%，多为表皮葡萄球菌和金黄色葡萄球菌，对万古霉素敏感；真菌感染占32.07%，多为白假丝酵母菌，对两性霉素B、氟康唑、5-氟胞嘧啶敏感。结论老年糖尿病患者易罹患肺部感染、混合感染，病原菌耐药性增强，其治疗在严格控制血糖基础上，根据病原菌的特点选择敏感有效的抗生素治疗，有利于病情控制，对提高糖尿病患者的生活质量，降低病死率有着极其重要作用。
目的：探討老年糖尿病患者閤併肺部感染的病原菌分佈特點和藥敏試驗情況，以便為臨床用藥提供依據。方法選取2005年8月～2010年12月武警湖南總隊醫院收治的老年糖尿病閤併肺部感染患者76例的痰標本，培養、分離病原菌。結果76例患者檢齣53株病原菌，其中革蘭陰性菌佔37.74%，多為大腸埃希菌、肺炎剋雷伯菌桿菌，對亞胺培南、喹諾酮類抗生素敏感；革蘭暘性菌佔30.19%，多為錶皮葡萄毬菌和金黃色葡萄毬菌，對萬古黴素敏感；真菌感染佔32.07%，多為白假絲酵母菌，對兩性黴素B、氟康唑、5-氟胞嘧啶敏感。結論老年糖尿病患者易罹患肺部感染、混閤感染，病原菌耐藥性增彊，其治療在嚴格控製血糖基礎上，根據病原菌的特點選擇敏感有效的抗生素治療，有利于病情控製，對提高糖尿病患者的生活質量，降低病死率有著極其重要作用。
목적：탐토노년당뇨병환자합병폐부감염적병원균분포특점화약민시험정황，이편위림상용약제공의거。방법선취2005년8월～2010년12월무경호남총대의원수치적노년당뇨병합병폐부감염환자76례적담표본，배양、분리병원균。결과76례환자검출53주병원균，기중혁란음성균점37.74%，다위대장애희균、폐염극뢰백균간균，대아알배남、규낙동류항생소민감；혁란양성균점30.19%，다위표피포도구균화금황색포도구균，대만고매소민감；진균감염점32.07%，다위백가사효모균，대량성매소B、불강서、5-불포밀정민감。결론노년당뇨병환자역리환폐부감염、혼합감염，병원균내약성증강，기치료재엄격공제혈당기출상，근거병원균적특점선택민감유효적항생소치료，유리우병정공제，대제고당뇨병환자적생활질량，강저병사솔유착겁기중요작용。
Objective To evaluate the pathogen distribution of diabetes mellitus complicated with pulmonary infection in the elderly patients and its drug sensitivity test, in order to provide the basis for the clinical medication.Methods We extracted the sputum samples from 76 elderly diabetes mellitus patients complicated with pulmonary infection, and cultured, separated the pathogenic bacteria.Results 53 strains of pathogenic bacteria were detected in 76 patients, in which the gram-negative bacilli accounted for 37.74%, including escherichia coli and klebsiella pneumoniae, sensitive to imipenem and quinolones; The gram-positive bacilli accounted for 30.19%, including staphylococcus epidermidis and staphylococcus aureus, sensitive to vancomycin;The fungal infection accounted for for 32.07%, including candida albicans, sensitive to amphotericin B, lfuconazole and 5- lfucytosine.Conclusion Obviously the elderly diabetic mellitus patients are susceptible to pulmonary infection and mixed infection, with drug resistance enhanced.In order to improve the life quality of diabetes mellitus patients, and decrease the mortality rate, it is extremely important to select sensitive and effective antibiotic therapy according to the characteristics of pathogenic bacteria, in the basis of strict glycemic control.
