CAJ | 학술논문

三氧化聚合物（MTA）和波特兰水门汀（PC）均含有氧化钙，氧化钙与水反应生成氢氧化钙，这样的一个高碱性环境抑制细菌的生长。灰色波特兰水门汀（GPC）中对人体危害的重金属元素铅、砷和铬的质量较白色波特兰水门汀（WPC）和MTA多。根管充填材料的溶解性影响根管充填的封闭性，总体而言，MTA和PC的根尖封闭性能相当。良好的口腔材料应具有适当的凝固时间，在MTA和PC中加入氯化钙或甲酸钙可缩短凝固时间。材料微粒的大小可影响其封闭性、凝固时间、抗压强度和耐磨性能等。WPC的平均粒径大于MTA，其抗压强度小于MTA，但是加有金粉的WPC的抗压强度与MTA相当。MTA和PC皆无细胞毒性和遗传毒性，两者对中国仓鼠卵巢细胞的DNA的影响无差异。MTA和PC对藤黄微球菌、金黄色葡萄球菌和大肠埃希菌等多种微生物有抑菌性能。MTA和PC均可促硬组织矿化，皆可导致牙体牙冠变色，但PC的变色轻于MTA。MTA因凝固时间长、牙体变色、不易取出和价格昂贵等，使其应用受限；而PC则可以作为一种经济的有效的MTA替代材料应用于牙体修复，但其远期疗效还不确定，需要更长时间的随访评估。
삼양화취합물（MTA）화파특란수문정（PC）균함유양화개，양화개여수반응생성경양화개，저양적일개고감성배경억제세균적생장。회색파특란수문정（GPC）중대인체위해적중금속원소연、신화락적질량교백색파특란수문정（WPC）화MTA다。근관충전재료적용해성영향근관충전적봉폐성，총체이언，MTA화PC적근첨봉폐성능상당。량호적구강재료응구유괄당적응고시간，재MTA화PC중가입록화개혹갑산개가축단응고시간。재료미립적대소가영향기봉폐성、응고시간、항압강도화내마성능등。WPC적평균립경대우MTA，기항압강도소우MTA，단시가유금분적WPC적항압강도여MTA상당。MTA화PC개무세포독성화유전독성，량자대중국창서란소세포적DNA적영향무차이。MTA화PC대등황미구균、금황색포도구균화대장애희균등다충미생물유억균성능。MTA화PC균가촉경조직광화，개가도치아체아관변색，단PC적변색경우MTA。MTA인응고시간장、아체변색、불역취출화개격앙귀등，사기응용수한；이PC칙가이작위일충경제적유효적MTA체대재료응용우아체수복，단기원기료효환불학정，수요경장시간적수방평고。
Mineral trioxide aggregate(MTA) and Portland cement(PC) contain calcium oxide, which reacts with water to form calcium hydroxide and producesa highly alkaline environment that inhibits bacterial growth. Compared with white PC(WPC) and MTA, gray Portland cement(GPC) has high concentrations of harmful heavy metals, namely arsenic, chromium, and lead. The solubility of root-canal filling affects itsability to close. The overall apical closure performances of MTA and PC are relatively similar. Good oral materials should have appropriate setting times. Addition of calcium chloride or calcium formate to MTA and PC shortens their setting time. The particle size of the material also affects its closure, setting time, compressive strength, and abrasion resistance. The average particle size of WPC is greater than that of MTA; however, the compressive strength of the former is lower than that of the latter. When mixed with gold powder, the compressive strength of WPC is similar to that of MTA. MTA and PC are non-toxic and genotoxic, and their toxicities to Chinese hamster ovary cells showno significant difference. Moreover, MTA and PC exhibit antibacterial activities toward Micrococcus luteus, Staphylococcus aureus, Escherichia coli, and other microorganisms. MTA and PC can promote hard tissue mineralization, which can leadto crown discolorations; PC results in lighter colors compared with those observed from MTA. Applications of MTA are limited by its long setting time, tooth discoloration, high-cost, and difficultyof removal. Thus, PC can be an economical alternative to MTA for dental restoration. The long-term effects of this material, however, are still uncertain and require longer assessments.