中西医结合心血管病电子杂志
中西醫結閤心血管病電子雜誌
중서의결합심혈관병전자잡지
Cardiovascular Disease Journal of Integrated Traditional Chinese and Western Medicine (Electronic)
2014年
7期
20-20,21
,共2页
精神分裂症%抗精神病药物%脂肪肝%B超
精神分裂癥%抗精神病藥物%脂肪肝%B超
정신분렬증%항정신병약물%지방간%B초
Schizophrenia%Antipsychotics%Fatty Liver%Type-B Ultrasonic
目的：观察长期服用抗精神病药物治疗的精神分裂症患者伴发脂肪肝的B超检查情况。方法利用B超观察228例长期服用抗精神病药物的精神分裂症患者的肝脏情况，并检测其血脂及肝功能情况。结果服用抗精神病药物的精神分裂症患者伴发脂肪肝的比例为32．5％，且脂肪肝的患病率与用药年限呈显著相关，脂肪肝患者甘油三酯，谷丙酰氨基转移酶显著增高。结论长期服用抗精神病药物治疗的精神分裂症患者伴发脂肪肝的比例较高，定期进行肝脏B超检查，血脂、肝功能检测对指导临床早期发现脂肪肝以及合理用药有重要意义。
目的：觀察長期服用抗精神病藥物治療的精神分裂癥患者伴髮脂肪肝的B超檢查情況。方法利用B超觀察228例長期服用抗精神病藥物的精神分裂癥患者的肝髒情況，併檢測其血脂及肝功能情況。結果服用抗精神病藥物的精神分裂癥患者伴髮脂肪肝的比例為32．5％，且脂肪肝的患病率與用藥年限呈顯著相關，脂肪肝患者甘油三酯，穀丙酰氨基轉移酶顯著增高。結論長期服用抗精神病藥物治療的精神分裂癥患者伴髮脂肪肝的比例較高，定期進行肝髒B超檢查，血脂、肝功能檢測對指導臨床早期髮現脂肪肝以及閤理用藥有重要意義。
목적：관찰장기복용항정신병약물치료적정신분렬증환자반발지방간적B초검사정황。방법이용B초관찰228례장기복용항정신병약물적정신분렬증환자적간장정황，병검측기혈지급간공능정황。결과복용항정신병약물적정신분렬증환자반발지방간적비례위32．5％，차지방간적환병솔여용약년한정현저상관，지방간환자감유삼지，곡병선안기전이매현저증고。결론장기복용항정신병약물치료적정신분렬증환자반발지방간적비례교고，정기진행간장B초검사，혈지、간공능검측대지도림상조기발현지방간이급합리용약유중요의의。
Objective To investigate the long-term use of antipsychotics in schizophrenic patients treated with fatty liver associated with B-inspec-tion. Methods B-observed 228 cases of liver situation long-term use of antipsychotics in schizophrenic patients and their lipid and liver function detects the situation. Results The proportion of patients with schizophrenia taking antipsychotics associated with fatty liver was 32. 5%,and the prevalence of fatty liver with medication age was significantly associated with fatty liver triglyceride (TG ), alanine amidotransferase enzymes (ALT ) increased significantly. Conclusion Long-term use of antipsychotics in schizophrenic patients treated with a higher proportion of fat fatty liver,liver regular B-ultrasound,blood lip-ids,liver function tests for the early detection of clinical fatty liver and rational use of drugs is important.
