CAJ | 학술논문

目的：研究伽玛刀放射外科治疗原发性三叉神经痛的长期有效性和安全性。方法：对随访时间超过60个月、仅接受过1次伽玛刀放射外科治疗的原发性三叉神经痛患者进行回顾性分析，总结患者的长期疼痛控制率、并发症发生率并进行相关因素分析。结果：对69例患者的平均随访时间为92个月。疼痛控制率I级14例(占20.3%)；II级10例(占14.5%)；III级26例(占37.7%)；IV级13例(占18.8%)；V级6例(占8.7%)。11例(占15.9%)患者出现面部感觉异常，无严重不良反应。患者的年龄、性别及疼痛的部位不影响伽玛刀的疗效。结论：伽玛刀放射外科治疗三叉神经痛疗效确切，不良反应发生率低，是不能耐受手术患者的较好治疗方式。
목적：연구가마도방사외과치료원발성삼차신경통적장기유효성화안전성。방법：대수방시간초과60개월、부접수과1차가마도방사외과치료적원발성삼차신경통환자진행회고성분석，총결환자적장기동통공제솔、병발증발생솔병진행상관인소분석。결과：대69례환자적평균수방시간위92개월。동통공제솔I급14례(점20.3%)；II급10례(점14.5%)；III급26례(점37.7%)；IV급13례(점18.8%)；V급6례(점8.7%)。11례(점15.9%)환자출현면부감각이상，무엄중불량반응。환자적년령、성별급동통적부위불영향가마도적료효。결론：가마도방사외과치료삼차신경통료효학절，불량반응발생솔저，시불능내수수술환자적교호치료방식。
Objective:To assess the long-term safety and efficacy of gamma knife radiosurgery for treatment of typical trigeminal neuralgia (TN). Methods: Retrospectively analyzed the typical trigeminal neuralgia patients who received only single gamma knife radiosurgery treatment and the follow-up time for more than 60 months, To assess the long-term safety and efficacy of the treatment for TN, the related factors were analyzed at last. Results: A total of 69 patients were enrolled in this study and the mean follow-up time were 92 months(60-128 months). According to the pain intensity scale at the last follow-up, 14 cases(20.3%) were grade I, 10 cases(14.5%) were grade II, 26 cases(37.7%) were grade III, 13 cases(18.8%) were grade IV and 6 cases(8.7%) were grade V. Facial sensory dysfunction occurred in 15.9%of patients, but no serious treatment-related complications were found. The age, sex and pain site does not affect the gamma knife’s efficacy. Conclusion:Gamma knife radiosurgery is a safe and effective long-term treatment method for TN and should be considered as an alternative option for the patients who cannot tolerate invasive surgery.