目的:观察眼轴长度对非增殖期糖尿病视网膜病变( nonproliferative diabetic retinopathy,NPDR)眼部彩色多普勒血流动力学的影响。
<br> 方法:前瞻性比较病例系例。自2012-01/2013-12间我院眼科及内分泌科住院的糖尿病视网膜病变患者,排除中心视网膜有明显的水肿、出血、渗出及有明显的其它眼底病变者,依据眼科A/B超测量眼球轴长并根据眼轴长度将患者归类为眼轴长度正常组(22~<24 mm )、长眼轴组(24~<26mm)及超长眼轴组(26mm及以上),所有患者进行眼部彩色多普勒血流动力学指标测定,对有完整研究资料的患者248例248眼的研究指标进行统计学分析,观察眼轴长度与眼部彩色多普勒血流动力学指标的相关性。
<br> 结果:正常眼轴组与长眼轴组比较,长眼轴组OA的PSV (cm/s)无明显变化(t=1.362,P=0.20)、CRA 的 PSV (cm/s)较高(t=-2.335,P=0.02),PCA的PSV(cm/s)较高(t=2.756,P=0.01),PI(t=-2.371,-2.585,-2.67;P=0.02,0.01,0.01)及RI( t=2.348,2.462,2.293;P=0.02,0.01,0.03)相对较低,差异均有统计学意义(P<0.05)。正常眼轴组与超长眼轴组比较,超长眼轴组OA的PSV较低(t=3.290,P=0.00),CRA及PCA的PSV(t=-5.520,-4.900;P=0.00,0.00)高;PI(t=4.970,6.160,5.990;P=0.00,0.00,0.00);RI(t=-4.310,-5.230,-4.390;P=0.00,0.00,0.00)低,差异有统计学意义(P<0.01)。长眼轴组与超长眼轴组比较,超长眼轴组OA的PSV(cm/s)较慢,但两者比较无统计学意义(t=1.967,P=0.07)、CRA的PSV (cm/s)较低(t=-2.543,P=0.01),PCA的PSV(cm/s)较高(t=-2.198,P=0.04),PI(t=-2.331,-2.135,-4.191;P=0.03,0.03,0.00)及RI(t=2.570,2.360,2.490;P=0.01,0.02,0.01)相对较低,差异均有统计学意义(P<0.05)。
<br> 结论:糖尿病视网膜病变患者的眼轴长度与眼部彩色多普勒血流动力学指标有着明显的相关性。
目的:觀察眼軸長度對非增殖期糖尿病視網膜病變( nonproliferative diabetic retinopathy,NPDR)眼部綵色多普勒血流動力學的影響。
<br> 方法:前瞻性比較病例繫例。自2012-01/2013-12間我院眼科及內分泌科住院的糖尿病視網膜病變患者,排除中心視網膜有明顯的水腫、齣血、滲齣及有明顯的其它眼底病變者,依據眼科A/B超測量眼毬軸長併根據眼軸長度將患者歸類為眼軸長度正常組(22~<24 mm )、長眼軸組(24~<26mm)及超長眼軸組(26mm及以上),所有患者進行眼部綵色多普勒血流動力學指標測定,對有完整研究資料的患者248例248眼的研究指標進行統計學分析,觀察眼軸長度與眼部綵色多普勒血流動力學指標的相關性。
<br> 結果:正常眼軸組與長眼軸組比較,長眼軸組OA的PSV (cm/s)無明顯變化(t=1.362,P=0.20)、CRA 的 PSV (cm/s)較高(t=-2.335,P=0.02),PCA的PSV(cm/s)較高(t=2.756,P=0.01),PI(t=-2.371,-2.585,-2.67;P=0.02,0.01,0.01)及RI( t=2.348,2.462,2.293;P=0.02,0.01,0.03)相對較低,差異均有統計學意義(P<0.05)。正常眼軸組與超長眼軸組比較,超長眼軸組OA的PSV較低(t=3.290,P=0.00),CRA及PCA的PSV(t=-5.520,-4.900;P=0.00,0.00)高;PI(t=4.970,6.160,5.990;P=0.00,0.00,0.00);RI(t=-4.310,-5.230,-4.390;P=0.00,0.00,0.00)低,差異有統計學意義(P<0.01)。長眼軸組與超長眼軸組比較,超長眼軸組OA的PSV(cm/s)較慢,但兩者比較無統計學意義(t=1.967,P=0.07)、CRA的PSV (cm/s)較低(t=-2.543,P=0.01),PCA的PSV(cm/s)較高(t=-2.198,P=0.04),PI(t=-2.331,-2.135,-4.191;P=0.03,0.03,0.00)及RI(t=2.570,2.360,2.490;P=0.01,0.02,0.01)相對較低,差異均有統計學意義(P<0.05)。
<br> 結論:糖尿病視網膜病變患者的眼軸長度與眼部綵色多普勒血流動力學指標有著明顯的相關性。
목적:관찰안축장도대비증식기당뇨병시망막병변( nonproliferative diabetic retinopathy,NPDR)안부채색다보륵혈류동역학적영향。
<br> 방법:전첨성비교병례계례。자2012-01/2013-12간아원안과급내분비과주원적당뇨병시망막병변환자,배제중심시망막유명현적수종、출혈、삼출급유명현적기타안저병변자,의거안과A/B초측량안구축장병근거안축장도장환자귀류위안축장도정상조(22~<24 mm )、장안축조(24~<26mm)급초장안축조(26mm급이상),소유환자진행안부채색다보륵혈류동역학지표측정,대유완정연구자료적환자248례248안적연구지표진행통계학분석,관찰안축장도여안부채색다보륵혈류동역학지표적상관성。
<br> 결과:정상안축조여장안축조비교,장안축조OA적PSV (cm/s)무명현변화(t=1.362,P=0.20)、CRA 적 PSV (cm/s)교고(t=-2.335,P=0.02),PCA적PSV(cm/s)교고(t=2.756,P=0.01),PI(t=-2.371,-2.585,-2.67;P=0.02,0.01,0.01)급RI( t=2.348,2.462,2.293;P=0.02,0.01,0.03)상대교저,차이균유통계학의의(P<0.05)。정상안축조여초장안축조비교,초장안축조OA적PSV교저(t=3.290,P=0.00),CRA급PCA적PSV(t=-5.520,-4.900;P=0.00,0.00)고;PI(t=4.970,6.160,5.990;P=0.00,0.00,0.00);RI(t=-4.310,-5.230,-4.390;P=0.00,0.00,0.00)저,차이유통계학의의(P<0.01)。장안축조여초장안축조비교,초장안축조OA적PSV(cm/s)교만,단량자비교무통계학의의(t=1.967,P=0.07)、CRA적PSV (cm/s)교저(t=-2.543,P=0.01),PCA적PSV(cm/s)교고(t=-2.198,P=0.04),PI(t=-2.331,-2.135,-4.191;P=0.03,0.03,0.00)급RI(t=2.570,2.360,2.490;P=0.01,0.02,0.01)상대교저,차이균유통계학의의(P<0.05)。
<br> 결론:당뇨병시망막병변환자적안축장도여안부채색다보륵혈류동역학지표유착명현적상관성。
AIM: To observe the effect of axial length on color Doppler hemodynamic of nonproliferative diabetic retinopathy (NPDR) eye.
<br> METHODS: This is a prospective comparative case series study. The hospitalized patients with diabetic retinopathy from January 2012 to December 2013 in Department of Ophthalmology and Endocrinology of our hospital were included, those with central retinal significant edema, hemorrhage, exudation and significant other fundus lesions were excluded. According to ocular axial length measured by ophthalmologic A / B ultrasound scanner and axial length, the patients were divided into normal axial group (22 ~ <24mm), long axial group (24 ~<26mm) and super- long axial group (26mm or above). Color Doppler hemodynamic parameters of all patients were measured. Totally, 248 cases ( 248 eyes ) with complete research data were statistically analyzed and were observed the correlation between axial length and eye color Doppler hemodynamics.
<br> RESULTS:Compared with normal axial group, OA PSV (cm/s) of long axial group did not change significantly (t=1.362, P=0.20), CRA PSV (cm/s) was high (t=-2.335, P=0.02), PCA PSV (cm/s) was higher (t=2. 756, P=0. 01), PI (t=-2. 371, -2. 585, -2. 67;P=0. 02, 0. 01, 0. 01) and RI (t= 2. 348, 2. 462, 2. 293;P=0. 02, 0. 01, 0. 03) is relatively lower, there were statistically significant differences ( P<0. 05). When compared with super-long axial group, ultra long shaft section OA(t=3. 290,P=0. 00) low, CRA and PCA PSV of normal axial group was higher (t=3. 290,-5.520, -4.900;P=0.00, 0.00, 0.00), PI (t=4.970,6.160, 5.990; P=0.00, 0.00, 0.00) and RI (t=-4.310, -5.230,-4. 390; P = 0. 00, 0. 00, 0. 00 ) was lower, there was statistically significant differences ( P < 0.005 ) . When compared with long axial group, OA in PSV ( cm/s ) of super-long axial group was more slower, but with no statistical significance (t=1. 967, P=0. 07), CRA PSV (cm/s) was lower (t=-2. 543, P=0. 01), PCA PSV (cm/s) was higher (t=-2.198, P=0.04), PI (t=-2.331,-2.135, -4.191;P=0.03, 0.03, 0. 00) and RI (t=2. 570, 2.360, 2. 490;P=0. 01, 0. 02, 0. 01 ) was relatively lower, there were significant differences (P<0. 05).
<br> CONCLUSION: There is a clear correlation between axial length in diabetic retinopathy and ocular hemodynamics with color Doppler index.