国际眼科杂志
國際眼科雜誌
국제안과잡지
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
2014年
11期
2059-2061
,共3页
高度近视%角膜厚度%角膜内皮细胞
高度近視%角膜厚度%角膜內皮細胞
고도근시%각막후도%각막내피세포
high myopia%central corneal thickness%corneal endothelium
目的：分析增龄性高度近视眼患者角膜内皮细胞生物学特性。
<br> 方法：将189例197眼年龄≥65岁的患者按屈光度数分为高度近视眼组和正常对照组,其中高度近视眼组98例103眼,正常对照组91例94眼。应用非接触式自动角膜内皮计测量两组患者角膜内皮细胞的六角形细胞比率(6A)、变异系数( CV)、平均面积( AVE)、平均密度( CD)及中央角膜厚度( CCT ), SPSS 14.0统计分析软件对两组所测得数据进行统计学分析,两样本均数的比较采用 Z检验,率的比较采用χ2检验。
<br> 结果：高度近视眼患者角膜内皮细胞平均密度减小,但密度>3000个/mm2者14眼,对照组为0眼；密度<2000个/mm2者11眼,对照组为3眼,2000~3000个/mm2者78眼,对照组为91眼,内皮细胞平均密度分布两组比较有显著性差异(χ2=19.11,P<0.05)。同时高度近视眼患者角膜内皮六角形细胞比率降低、细胞变异系数增大,平均面积增大,两组比较均有显著性差异(P<0.05),中央角膜厚度两组间比较无显著性差异(P>0.05)。
<br> 结论：根据角膜内皮的细胞参数和形态学的变化,可以了解内皮的功能储备,预测愈后,借以决定某种手术的设计和取舍,对临床手术医师是一种很有价值的参考指标。
目的：分析增齡性高度近視眼患者角膜內皮細胞生物學特性。
<br> 方法：將189例197眼年齡≥65歲的患者按屈光度數分為高度近視眼組和正常對照組,其中高度近視眼組98例103眼,正常對照組91例94眼。應用非接觸式自動角膜內皮計測量兩組患者角膜內皮細胞的六角形細胞比率(6A)、變異繫數( CV)、平均麵積( AVE)、平均密度( CD)及中央角膜厚度( CCT ), SPSS 14.0統計分析軟件對兩組所測得數據進行統計學分析,兩樣本均數的比較採用 Z檢驗,率的比較採用χ2檢驗。
<br> 結果：高度近視眼患者角膜內皮細胞平均密度減小,但密度>3000箇/mm2者14眼,對照組為0眼；密度<2000箇/mm2者11眼,對照組為3眼,2000~3000箇/mm2者78眼,對照組為91眼,內皮細胞平均密度分佈兩組比較有顯著性差異(χ2=19.11,P<0.05)。同時高度近視眼患者角膜內皮六角形細胞比率降低、細胞變異繫數增大,平均麵積增大,兩組比較均有顯著性差異(P<0.05),中央角膜厚度兩組間比較無顯著性差異(P>0.05)。
<br> 結論：根據角膜內皮的細胞參數和形態學的變化,可以瞭解內皮的功能儲備,預測愈後,藉以決定某種手術的設計和取捨,對臨床手術醫師是一種很有價值的參攷指標。
목적：분석증령성고도근시안환자각막내피세포생물학특성。
<br> 방법：장189례197안년령≥65세적환자안굴광도수분위고도근시안조화정상대조조,기중고도근시안조98례103안,정상대조조91례94안。응용비접촉식자동각막내피계측량량조환자각막내피세포적륙각형세포비솔(6A)、변이계수( CV)、평균면적( AVE)、평균밀도( CD)급중앙각막후도( CCT ), SPSS 14.0통계분석연건대량조소측득수거진행통계학분석,량양본균수적비교채용 Z검험,솔적비교채용χ2검험。
<br> 결과：고도근시안환자각막내피세포평균밀도감소,단밀도>3000개/mm2자14안,대조조위0안；밀도<2000개/mm2자11안,대조조위3안,2000~3000개/mm2자78안,대조조위91안,내피세포평균밀도분포량조비교유현저성차이(χ2=19.11,P<0.05)。동시고도근시안환자각막내피륙각형세포비솔강저、세포변이계수증대,평균면적증대,량조비교균유현저성차이(P<0.05),중앙각막후도량조간비교무현저성차이(P>0.05)。
<br> 결론：근거각막내피적세포삼수화형태학적변화,가이료해내피적공능저비,예측유후,차이결정모충수술적설계화취사,대림상수술의사시일충흔유개치적삼고지표。
AIM: To analyze quantitatively the biological characteristics of corneal endothelium in old patients of high myopia with non - contact automatic corneal endothelial microscope.
<br> METHODS:A total of 189 old patients ( 197 eyes ) were divided into the high myopia group and the normal control group according to refractive diopter, in which the former 98 cases (103 eyes), the latter 91 cases (94 eyes). The hexagonal cell ( 6A ), the coefficient of variation ( CV ) , the average cell area ( AVE ) , the average cell density ( CD ) and the central corneal thickness ( CCT ) were measured by non - contact automatic corneal endothelium. SPSS 14. 0 software was used to analyze their percentage. Z-test was used to compare the mean and Chi-square test was used to compare the rate in between.
<br> RESULTS: The average cell density in high myopia patients decreased, but there were 14 eyes >3 000/mm2 , 11 eyes <2 000/mm2 and 78 eyes in the 2 000 ~3 000/mm2 , there were each 0 eye, 3 eyes and 91 eyes respectively in the normal control group. There was statistically significant difference between high myopia group and control (χ2=19. 11, P<0. 05). Meanwhile the percentage of the hexagonal cell decreased, the coefficient of variation and the average cell area increased. There was statistically significant difference between high myopia group and control (P<0. 05). There was no statistically significant difference in the central corneal thickness between the two groups (P>0. 05).
<br> CONCLUSION: There will provide a reference valuable for clinical surgeon. Because according to the changes of parameters and morphology of the corneal endothelial cells, we can understand the repair ability, to predict the consequence of the treatment, in order to determine the design and the choice of a surgical.
