国际眼科杂志
國際眼科雜誌
국제안과잡지
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
2014年
11期
2012-2015
,共4页
邓宏伟%谢辉庭%贾惠莉%钟华红%陈青山%成洪波
鄧宏偉%謝輝庭%賈惠莉%鐘華紅%陳青山%成洪波
산굉위%사휘정%가혜리%종화홍%진청산%성홍파
斜视性弱视%视网膜色素上皮层%黄斑%神经节细胞复合体厚度
斜視性弱視%視網膜色素上皮層%黃斑%神經節細胞複閤體厚度
사시성약시%시망막색소상피층%황반%신경절세포복합체후도
strabismic amblyopia%retinal pigmented epithelium%macula%ganglion cell complex thickness
目的：通过检测单眼斜视性弱视患者双眼黄斑区视网膜神经节细胞复合体厚度,探讨弱视的程度与视网膜神经节细胞厚度的相关性,以及斜视性弱视患者黄斑区神经节细胞复合体结构是否存在异常。
<br> 方法：选取临床单眼斜视性弱视患者26例52眼。采用美国傅立叶域光学相干断层扫描仪( fourier-domain optical coherence tomography,FD-OCT) iVue同时检测双眼黄斑区神经节细胞复合体厚度,并比较黄斑区神经节细胞复合体厚度与患者最佳矫正视力的相关性。
<br> 结果：黄斑区神经节细胞复合体厚度( macular ganglion cell complex, mGCC )分为三个区域测量：中心区、内圈(3mm )区、外圈(6mm )区。在斜视性弱视的眼(strabismic amblyopia eye,SAE)测量结果分别是50.74±21.51,101.4±8.51,114.2±9.455μm；在对侧对照眼(contralateral sound eyes,CSE)测量结果分别是43.79±11.92,92.47±25.01,113.3±12.88μm。斜视性弱视眼的黄斑区视神经节细胞复合体厚度与对侧眼相比无显著差异(P>0.05)。最佳矫正视力与黄斑区神经节细胞复合体厚度有相关性,视力矫正越好弱视程度越低的黄斑区神经节细胞复合体厚度相对增厚,黄斑区下方区域的神经节细胞复合体厚度与视力矫正的相关性优于上方。
<br> 结论：黄斑中心区神经节细胞复合体厚度与弱视矫正视力之间有相关性,虽然mGCC厚度在SAE和CSE无显著差异,但测量mGCC厚度对了解弱视程度有临床意义。
目的：通過檢測單眼斜視性弱視患者雙眼黃斑區視網膜神經節細胞複閤體厚度,探討弱視的程度與視網膜神經節細胞厚度的相關性,以及斜視性弱視患者黃斑區神經節細胞複閤體結構是否存在異常。
<br> 方法：選取臨床單眼斜視性弱視患者26例52眼。採用美國傅立葉域光學相榦斷層掃描儀( fourier-domain optical coherence tomography,FD-OCT) iVue同時檢測雙眼黃斑區神經節細胞複閤體厚度,併比較黃斑區神經節細胞複閤體厚度與患者最佳矯正視力的相關性。
<br> 結果：黃斑區神經節細胞複閤體厚度( macular ganglion cell complex, mGCC )分為三箇區域測量：中心區、內圈(3mm )區、外圈(6mm )區。在斜視性弱視的眼(strabismic amblyopia eye,SAE)測量結果分彆是50.74±21.51,101.4±8.51,114.2±9.455μm；在對側對照眼(contralateral sound eyes,CSE)測量結果分彆是43.79±11.92,92.47±25.01,113.3±12.88μm。斜視性弱視眼的黃斑區視神經節細胞複閤體厚度與對側眼相比無顯著差異(P>0.05)。最佳矯正視力與黃斑區神經節細胞複閤體厚度有相關性,視力矯正越好弱視程度越低的黃斑區神經節細胞複閤體厚度相對增厚,黃斑區下方區域的神經節細胞複閤體厚度與視力矯正的相關性優于上方。
<br> 結論：黃斑中心區神經節細胞複閤體厚度與弱視矯正視力之間有相關性,雖然mGCC厚度在SAE和CSE無顯著差異,但測量mGCC厚度對瞭解弱視程度有臨床意義。
목적：통과검측단안사시성약시환자쌍안황반구시망막신경절세포복합체후도,탐토약시적정도여시망막신경절세포후도적상관성,이급사시성약시환자황반구신경절세포복합체결구시부존재이상。
<br> 방법：선취림상단안사시성약시환자26례52안。채용미국부립협역광학상간단층소묘의( fourier-domain optical coherence tomography,FD-OCT) iVue동시검측쌍안황반구신경절세포복합체후도,병비교황반구신경절세포복합체후도여환자최가교정시력적상관성。
<br> 결과：황반구신경절세포복합체후도( macular ganglion cell complex, mGCC )분위삼개구역측량：중심구、내권(3mm )구、외권(6mm )구。재사시성약시적안(strabismic amblyopia eye,SAE)측량결과분별시50.74±21.51,101.4±8.51,114.2±9.455μm；재대측대조안(contralateral sound eyes,CSE)측량결과분별시43.79±11.92,92.47±25.01,113.3±12.88μm。사시성약시안적황반구시신경절세포복합체후도여대측안상비무현저차이(P>0.05)。최가교정시력여황반구신경절세포복합체후도유상관성,시력교정월호약시정도월저적황반구신경절세포복합체후도상대증후,황반구하방구역적신경절세포복합체후도여시력교정적상관성우우상방。
<br> 결론：황반중심구신경절세포복합체후도여약시교정시력지간유상관성,수연mGCC후도재SAE화CSE무현저차이,단측량mGCC후도대료해약시정도유림상의의。
AIM: To detect the macular ganglion cell complex thickness in monocular strabismus amblyopia patients, in order to explore the relationship between the degree of amblyopia and retinal ganglion cell complex thickness, and found out whether there is abnormal macular ganglion cell structure in strabismic amblyopia.METHODS: Using a fourier-domain optical coherence tomography ( FD-OCT) instrument iVue襆( Optovue Inc, Fremont, CA), Macular ganglion cell complex (mGCC) thickness was measured and statistical the relation rate with the best vision acuity correction was compared Gman among 26 patients ( 52 eyes ) included in this study.
<br> RESULTS:The mean thickness of the mGCC in macular was investigated into three parts: centrial, inner circle (3mm) and outer circle (6mm). The mean thicknesses of mGCC in central, inner and outer circle was 50. 74±21.51μm, 101. 4 ± 8. 51μm, 114. 2 ± 9. 455μm in the strabismic amblyopia eyes (SAE), and 43. 79±11.92μm, 92. 47±25. 01μm, 113. 3±12. 88μm in the contralateral sound eyes ( CSE ) respectively. There was no statistically significant difference among the eyes ( P>0.05 ) . But the best corrected vision acuity had a good correlation rate between mGcc thicknesses, which was better relative for the lower part than the upper part.
<br> CONCLUSION:There is a relationship between the amblyopia vision acuity and the mGCC thickness. Although there has not statistically significant difference of the mGCC thickness compared with the SAE and CSE. To measure the macular center mGCC thickness in clinic may understand the degree of amblyopia.
