国际眼科杂志
國際眼科雜誌
국제안과잡지
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
2014年
11期
1987-1990
,共4页
原花青素%药理作用%角膜病%白内障%青光眼%视网膜病变%外伤性视神经病变%视疲劳
原花青素%藥理作用%角膜病%白內障%青光眼%視網膜病變%外傷性視神經病變%視疲勞
원화청소%약리작용%각막병%백내장%청광안%시망막병변%외상성시신경병변%시피로
proanthocyanidins%pharmacological effects%keratopathy%cataract%glaucoma%retinopathy%traumatic optic neuropathy%asthenopia
原花青素是一种广泛存在于自然界植物中的多酚化合物。它具有极强的抗氧化活性和自由基清除能力，并且具有高效、低毒和高生物利用率等优点，可起到降血压、降血脂、抗炎、抗肿瘤、抗衰老、抗疲劳以及预防心脑血管疾病等功效。本文综述了原花青素的理化性质、药理作用、毒理作用及其在眼科应用的最新研究进展，主要是在角膜病、白内障、青光眼、葡萄膜炎、视网膜病变、视神经病变、眼外伤及视疲劳等方面进行概述。相信在不久的将来能对其药物作用机制进一步阐明，发挥其更大的医用价值，为眼科临床应用提供更多经济且有效的药物。
原花青素是一種廣汎存在于自然界植物中的多酚化閤物。它具有極彊的抗氧化活性和自由基清除能力，併且具有高效、低毒和高生物利用率等優點，可起到降血壓、降血脂、抗炎、抗腫瘤、抗衰老、抗疲勞以及預防心腦血管疾病等功效。本文綜述瞭原花青素的理化性質、藥理作用、毒理作用及其在眼科應用的最新研究進展，主要是在角膜病、白內障、青光眼、葡萄膜炎、視網膜病變、視神經病變、眼外傷及視疲勞等方麵進行概述。相信在不久的將來能對其藥物作用機製進一步闡明，髮揮其更大的醫用價值，為眼科臨床應用提供更多經濟且有效的藥物。
원화청소시일충엄범존재우자연계식물중적다분화합물。타구유겁강적항양화활성화자유기청제능력，병차구유고효、저독화고생물이용솔등우점，가기도강혈압、강혈지、항염、항종류、항쇠로、항피로이급예방심뇌혈관질병등공효。본문종술료원화청소적이화성질、약리작용、독리작용급기재안과응용적최신연구진전，주요시재각막병、백내장、청광안、포도막염、시망막병변、시신경병변、안외상급시피로등방면진행개술。상신재불구적장래능대기약물작용궤제진일보천명，발휘기경대적의용개치，위안과림상응용제공경다경제차유효적약물。
Proanthocyanidins is an effective antioxidants and free radical scavenger derived from kinds of plants in nature. It has some advantages that high absorptivity and bioactivity, low toxicity, which contain broad pharmacological functions such as dropping high blood pressure, reducing blood fat, anti-inflammatory, anti-cancer, anti - aging, anti - fatigue and preventing cardiovascular and cerebrovascular diseases. In this paper, we summarized its physicochemical properties, pharmacologic action and the ophthalmological studies which mainly in keratopathy, cataract, glaucoma, uveitis, retinopathy, traumatic optic neuropathy and asthenopia. With the deeper research and more unequivocal in the pharmacological mechanism of proanthocyanidins, it should make the most of its values in medicine. And some more economical and effective drugs are expected to be provided for the clinical ophthalmology in the near future.
