CAJ | 학술논문

目的：测量单纯白内障与合并糖尿病白内障患者超声乳化术后黄斑区中心凹与不同象限视网膜神经纤维层厚度变化的特点。 　　方法：回顾性非随机临床对比研究。选择行超声乳化白内障手术的患者90例110眼,单纯白内障组32例40眼为A组,合并糖尿病无视网膜病变的28例35眼为B组,有非增生性糖尿病视网膜病变的30例35眼为C组。通过光学相干断层扫描仪测量比较术前及术后1,14,28 d黄斑区视网膜神经纤维层厚度。采用卡方检验、重复测量方差分析、SNK-q检验对数据进行检验。 　　结果：中心凹区：三组的中心凹均有增长(F=18.92,P<0.05),C组与A组、C组与B组间差异有统计学意义(P均<0.05)。各象限：三组上方、鼻侧、下方、颞侧象限随着时间均有增长( F=13.33,14.37,19.02,16.93, P 均<0.05),三组间比较鼻侧象限的增长无统计学意义,而上方、下方、颞侧比较C组与A组、C组与B组间差异有统计学意义(P均<0.05)。 　　结论：合并糖尿病视网膜病变的白内障患者行超声乳化术后黄斑中心凹区及各象限视网膜神经纤维层厚度在术后4 wk内明显增加,黄斑水肿发生率高,开始时间早,持续时间长,患者术后视力恢复严重受损。
목적：측량단순백내장여합병당뇨병백내장환자초성유화술후황반구중심요여불동상한시망막신경섬유층후도변화적특점。 　　방법：회고성비수궤림상대비연구。선택행초성유화백내장수술적환자90례110안,단순백내장조32례40안위A조,합병당뇨병무시망막병변적28례35안위B조,유비증생성당뇨병시망막병변적30례35안위C조。통과광학상간단층소묘의측량비교술전급술후1,14,28 d황반구시망막신경섬유층후도。채용잡방검험、중복측량방차분석、SNK-q검험대수거진행검험。 　　결과：중심요구：삼조적중심요균유증장(F=18.92,P<0.05),C조여A조、C조여B조간차이유통계학의의(P균<0.05)。각상한：삼조상방、비측、하방、섭측상한수착시간균유증장( F=13.33,14.37,19.02,16.93, P 균<0.05),삼조간비교비측상한적증장무통계학의의,이상방、하방、섭측비교C조여A조、C조여B조간차이유통계학의의(P균<0.05)。 　　결론：합병당뇨병시망막병변적백내장환자행초성유화술후황반중심요구급각상한시망막신경섬유층후도재술후4 wk내명현증가,황반수종발생솔고,개시시간조,지속시간장,환자술후시력회복엄중수손。
AIM:To measure the changes of macular retinal nerve fiber layer thickness at different quadrants and macular fovea in diabetic and nondiabetic patients after phacoemulsification. METHODS:This was a retrospective nonrandom clinical comparison study, 90 patients (110 eyes) who underwent phacoemulsification were recruited, nondiabetic patients (32 cases, 40 eyes) were in group A, in diabetic without diabetic retinopathy (28 cases, 35 eyes) were as group B, with non-proliferation diabetic retinopathy ( 30 cases, 35 eyes) were group C. Macular retinal nerve fiber layer thicknesses were collected by optical coherence tomography on the preoperative day and on postoperative 1st, 14th, 28th d. Statistical analysis of count data measurement data were done separately by the Chi-square test, variance analysis and SNK-q test. RESULTS: The foveal: There was significant increase could be detected among A, B, C (F=18. 92, P<0. 05), while group C showed significant difference as compared with groups A and B (P<0. 05). The quadrant:There was significant increase could be detected among A, B, C ( F=13. 33, 14. 37, 19. 02, 16. 93, P<0. 05 ). This was not statistically significant of nasal among A, B, C groups ( P>0. 05). However group C showed significant difference in the superior, the inferior, the temporal as compared with groups A and B (P<0. 05). CONCLUSION: Macular retinal nerve fiber layer thickness and macular fovea of patients with diabetic retinopathy were significant increased after phacoemulsification in 4wk, the incidence of macular edema is higher, the time earlier, the duration longer, the poorer visual recovery.