CAJ | 학술논문

研制了液相色谱-质谱( LC-MS)校准用利血平/甲醇水溶液标准物质。采用准确可靠的方法对利血平粉末纯度进行定值，用已确定值的利血平为溶质，甲醇水为溶剂，用重量-容量法制得利血平/甲醇水溶液。分别用F检验和回归曲线法对均匀性和稳定性进行考察，对定值结果的不确定度进行了评定。结果表明研制的利血平/甲醇水溶液标准物质具有良好的均匀性和稳定性，标准相对扩展不确定度为3%(k=2)。
연제료액상색보-질보( LC-MS)교준용리혈평/갑순수용액표준물질。채용준학가고적방법대리혈평분말순도진행정치，용이학정치적리혈평위용질，갑순수위용제，용중량-용량법제득리혈평/갑순수용액。분별용F검험화회귀곡선법대균균성화은정성진행고찰，대정치결과적불학정도진행료평정。결과표명연제적리혈평/갑순수용액표준물질구유량호적균균성화은정성，표준상대확전불학정도위3%(k=2)。
Standard solution of reserpine in methanol aqueous for LC-MS calibration was developed. The puriety of reserpine powder was certified with credible methods. The standard solution was prepared by weight-volumetric method using the reserpine powder as solute and the methanol aqueous as solvent. Uniformity and stability of standard solution was analyzed by F test and regression curve method respec-tively, the uncertainty of the results was evaluated. The result showed that uniformity and stability of the standard solution of reserpine in methanol aqueous was better, the relative standard uncertainty of concen-tration was 3%( k=2 ) .