CAJ | 학술논문

目的：探讨肝肾阴虚型与非肝肾阴虚型视神经脊髓炎( neuromyelitis optica,NMO)患者临床特点差异。方法回顾性分析73例NMO患者的中医证型及临床特点,并根据中医证型的不同将其分为肝肾阴虚组和非肝肾阴虚组。将两组性别比例、发病年龄、年复发率等进行分析比较。结果肝肾阴虚组NMO患者49例,非肝肾阴虚组24例。肝肾阴虚组患者均兼夹痰热瘀,非肝肾阴虚组证型以气虚、气血亏虚、痰瘀为主。与非肝肾阴虚组相比,肝肾阴虚组患者女性多,年复发率较高(P<0．05),首次发病累及视力或视力、脊髓同时受累者居多(P<0．05)。结论不同中医证型NMO患者临床特点存在一定差异。
목적：탐토간신음허형여비간신음허형시신경척수염( neuromyelitis optica,NMO)환자림상특점차이。방법회고성분석73례NMO환자적중의증형급림상특점,병근거중의증형적불동장기분위간신음허조화비간신음허조。장량조성별비례、발병년령、년복발솔등진행분석비교。결과간신음허조NMO환자49례,비간신음허조24례。간신음허조환자균겸협담열어,비간신음허조증형이기허、기혈우허、담어위주。여비간신음허조상비,간신음허조환자녀성다,년복발솔교고(P<0．05),수차발병루급시력혹시력、척수동시수루자거다(P<0．05)。결론불동중의증형NMO환자림상특점존재일정차이。
Objective To investigate the differences of clinical features in patients with Neuromy-elitis Optica ( NMO) between liver-kidney yin deficiency type and non liver-kidney yin deficiency type. Methods TCM syndrome types and clinical features of 73 patients with NMO were analyzed retrospective-ly. According to the TCM syndrome types, patients were divided into two groups:liver-kidney yin deficien-cy(LKYD) group and non-liver-kidney yin deficiency (NLKYD) group. Sex ratio, age of onset and the annual relapse rate of two groups were compared. Results There were 49 cases in LKYD group, and 24 cases in NLKYD group. The liver-kidney yin deficiency patients are always combined with phlegm, heat and blood stasis syndromes. In LKYD group, the key syndromes were qi deficiency, blood deficiency, phlegm and blood stasis. Compared with NLKYD patients, there were more female, higher annualized re-lapse rate (P<0. 05), and more invasion of vision or vision combining with spinal cord of the first onset (P<0. 05) in LKYD patients. Conclusion Different clinical features exit in NMO patients with different TCM syndrome types.