临床肺科杂志
臨床肺科雜誌
림상폐과잡지
JOUNAL OF CLINICAL PULMONARY MEDICINE
2014年
12期
2206-2207,2208
,共3页
慢性阻塞性肺病%脑梗死
慢性阻塞性肺病%腦梗死
만성조새성폐병%뇌경사
chronic obstructive pulmonary disease%cerebral infarction
目的：探讨慢性阻塞性肺疾病( CPOD)并发脑梗死的相关因素。方法选取2012-2014年间201例慢性阻塞性肺病( COPD)患者,均行头颅MRI或CT检查,血小板,血红蛋白,D-二聚体,纤维蛋白原,胆固醇,甘油三酯,ESR,CRP,血气分析,肺功能检查,以COPD合并脑梗死的患者为观察组(76例),COPD非合并脑梗死的患者为对照组(125例)。结果观察组与对照组相比,D-二聚体分别为(1035．23±304．21)和(362．4±256．01)μg/L,血红蛋白分别为(178．43±25．88)和(143．67±35．41) g/L,PaO2分别为(68．36±25．34)和(82．71±31．25)mmHg,PaCO2分别为(58．68±10．53)和(35．41±4．13)mmHg,肺功能检查重度阻塞性通气功能障碍比例分别为33．3%和25．1%,纤维蛋白原分别为(3．68± 0．36)和(2．56±0．42) g/L,两组间比较差异有统计学意义(P<0．01)。结论慢性阻塞性肺疾病是引起脑梗死的高危因素,这可能与慢性阻塞性肺病患者长期慢性缺氧,二氧化碳潴留,D-二聚体,血红蛋白及纤维蛋白原升高有关。
目的：探討慢性阻塞性肺疾病( CPOD)併髮腦梗死的相關因素。方法選取2012-2014年間201例慢性阻塞性肺病( COPD)患者,均行頭顱MRI或CT檢查,血小闆,血紅蛋白,D-二聚體,纖維蛋白原,膽固醇,甘油三酯,ESR,CRP,血氣分析,肺功能檢查,以COPD閤併腦梗死的患者為觀察組(76例),COPD非閤併腦梗死的患者為對照組(125例)。結果觀察組與對照組相比,D-二聚體分彆為(1035．23±304．21)和(362．4±256．01)μg/L,血紅蛋白分彆為(178．43±25．88)和(143．67±35．41) g/L,PaO2分彆為(68．36±25．34)和(82．71±31．25)mmHg,PaCO2分彆為(58．68±10．53)和(35．41±4．13)mmHg,肺功能檢查重度阻塞性通氣功能障礙比例分彆為33．3%和25．1%,纖維蛋白原分彆為(3．68± 0．36)和(2．56±0．42) g/L,兩組間比較差異有統計學意義(P<0．01)。結論慢性阻塞性肺疾病是引起腦梗死的高危因素,這可能與慢性阻塞性肺病患者長期慢性缺氧,二氧化碳潴留,D-二聚體,血紅蛋白及纖維蛋白原升高有關。
목적：탐토만성조새성폐질병( CPOD)병발뇌경사적상관인소。방법선취2012-2014년간201례만성조새성폐병( COPD)환자,균행두로MRI혹CT검사,혈소판,혈홍단백,D-이취체,섬유단백원,담고순,감유삼지,ESR,CRP,혈기분석,폐공능검사,이COPD합병뇌경사적환자위관찰조(76례),COPD비합병뇌경사적환자위대조조(125례)。결과관찰조여대조조상비,D-이취체분별위(1035．23±304．21)화(362．4±256．01)μg/L,혈홍단백분별위(178．43±25．88)화(143．67±35．41) g/L,PaO2분별위(68．36±25．34)화(82．71±31．25)mmHg,PaCO2분별위(58．68±10．53)화(35．41±4．13)mmHg,폐공능검사중도조새성통기공능장애비례분별위33．3%화25．1%,섬유단백원분별위(3．68± 0．36)화(2．56±0．42) g/L,량조간비교차이유통계학의의(P<0．01)。결론만성조새성폐질병시인기뇌경사적고위인소,저가능여만성조새성폐병환자장기만성결양,이양화탄저류,D-이취체,혈홍단백급섬유단백원승고유관。
Objective To investigate the possible mechanism of CPOD patients complicated with brain in-farction. Methods 201 COPD patients were selected at random, each of which were underwent brain MRI or CT, platelet, hemoglobin, D-dimer, cholesterol, triglyceride, ESR, CRP, blood gas analysis, and pulmonary function tests. 76 of them complicated with cerebral infarction were taken as the observation group. Results The level of D-dimer was (1035. 23 ± 304. 21) and (362. 4 ± 256. 01)μg/L, the level of hemoglobin was (178. 43 ± 25. 88) and (143. 67 ± 35. 41)g/L, the level of PaCO2 was (68. 36 ± 25. 34) and (82. 71 ± 31. 25) mmHg, and the level of PaCO2 was (58. 68 ± 10. 53) and (35. 41 ± 4. 13)mmHg respectively in the observation group and the control group. The ratio of severe obstructive ventilation dysfunction was 33. 3% and 25. 1% respectively in the observation group and the control group. The content of fibrinogen was (3. 68 ± 0. 36) and (2. 56 ± 0. 42) g/L respectively in the ob-servation group and the control group. Conclusion Chronic obstructive pulmonary disease is the high-risk factor causing cerebral infraction, which may be related to long time chronic hypoxia, hypercapnia, and high level of D-di-mer and hemoglobin.
