CAJ | 학술논문

目的：通过对OSAHS和高血压患者分组进行临床特征分析,进一步明确其临床特点及诊治对策。方法对明确诊断为OSAHS合并高血压(组1),单纯高血压(组2)及单纯OSAHS(组3)的三组患者进行一般情况、临床症状、血脂、PSG合并症进行比较分析。结果(1) BMI：组1较组2 P<0．05(2)合并症方面,三组间在合并糖尿病、高脂血症方面无明显差异,P>0．05．但组2较组1更易并发冠心病(P=0．000)。(3)临床症状和血脂方面,组1的打鼾、夜尿增多、白天嗜睡、记忆力减退、高脂血症均多于组2(P均<0．05),且打鼾症状明显多于组3(P<0．05)。(4) PSG监测、血压及Epworth嗜睡量表(ESS)方面,除鼾声指数和晨起血压以外,组1与组2有明显差异(P均<0．05)；且组1与组3的夜间最低血氧饱和度、ESS及晨起血压之间差异具有统计学意义(P均<0．05)。结论 OSAHS合并高血压患者具有独特的临床特征,尤其在打鼾、夜间最低血氧饱和度和ESS等方面表现更明显。
목적：통과대OSAHS화고혈압환자분조진행림상특정분석,진일보명학기림상특점급진치대책。방법대명학진단위OSAHS합병고혈압(조1),단순고혈압(조2)급단순OSAHS(조3)적삼조환자진행일반정황、림상증상、혈지、PSG합병증진행비교분석。결과(1) BMI：조1교조2 P<0．05(2)합병증방면,삼조간재합병당뇨병、고지혈증방면무명현차이,P>0．05．단조2교조1경역병발관심병(P=0．000)。(3)림상증상화혈지방면,조1적타한、야뇨증다、백천기수、기억력감퇴、고지혈증균다우조2(P균<0．05),차타한증상명현다우조3(P<0．05)。(4) PSG감측、혈압급Epworth기수량표(ESS)방면,제한성지수화신기혈압이외,조1여조2유명현차이(P균<0．05)；차조1여조3적야간최저혈양포화도、ESS급신기혈압지간차이구유통계학의의(P균<0．05)。결론 OSAHS합병고혈압환자구유독특적림상특정,우기재타한、야간최저혈양포화도화ESS등방면표현경명현。
Objective To analyze the clinical characteristics of OSAHS and hypertension in order to clear its clinical features and treatment countermeasures. Methods The study selected OSAHS complicated with hypertension patients as the group A, simple hypertension patients as the group B and OSAHS alone as the group C. Their clinical symptoms, serum lipids, and PSG complications were comparatively analyzed. Results There was no significant difference in complications of diabetes and hyperlipemia among the three groups ( P>0. 05 ) , but the incidence of coronary heart disease was higher in the group B more than in the group A. The clinical symptoms of snoring, night urination, daytime drowsiness, memory loss and hyperlipidemia were all more serious in the group A than in the group B (P<0. 05). In terms of PSG monitoring, blood lipids and epworth sleepiness scale (ESS), there were significant differences between the groups A and B excluding snoring index and early morning blood pressure. Conclusion OS-AHS patients complicated with hypertension has special clinical features, especially in snoring, night lowest oxygen saturation, and ESS.