CAJ | 학술논문

目的：通过文献查阅总结葛花异黄酮的药理作用。方法应用中国知网等数据库检索系统，检索出中外相关研究文献，再分析综述。结果在葛花中先后分离得到了二十几种异黄酮化合物，葛花异黄酮及其苷元在解酒、护肝、抗肿瘤、抗炎、抗氧化等方面发挥药理作用，同时具有雌激素样活性。结论葛花异黄酮苷元在多种生物活性功能方面强于花异黄酮苷，更具临床应用价值。可以通过酸水解和酶水解的形式提高葛花异黄酮的生物利用率。
목적：통과문헌사열총결갈화이황동적약리작용。방법응용중국지망등수거고검색계통，검색출중외상관연구문헌，재분석종술。결과재갈화중선후분리득도료이십궤충이황동화합물，갈화이황동급기감원재해주、호간、항종류、항염、항양화등방면발휘약리작용，동시구유자격소양활성。결론갈화이황동감원재다충생물활성공능방면강우화이황동감，경구림상응용개치。가이통과산수해화매수해적형식제고갈화이황동적생물이용솔。
About twenty isoflavone components have been found in flos pueraria. The isoflavone and its aglycone in flos pueraria have pharmacological effects on the aspects of anti-alcohol liver protection anti-cancer anti-inflammation and antioxidant. And they also have estrogen-like activities. The aglycone was found more bioactive than isoflavone in flos pueraria. So the aglycone is more valuable in clinic. Methods of acid hydrolysis and enzyme hydrolysis should be used to improve the bioavailability of isoflavone in flos pueraria.