中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2014年
29期
15-16
,共2页
依托咪酯%丙泊酚%舒芬太尼%流产%麻醉
依託咪酯%丙泊酚%舒芬太尼%流產%痳醉
의탁미지%병박분%서분태니%유산%마취
Etomidate%Propfol%Sulfentanyl%Abortion%Anesthesia
目的：观察依托咪酯和丙泊酚混合液在无痛人流中的麻醉效果。方法选择门诊ASAⅠ~Ⅱ级自愿接受无痛人工流产手术的患者80例，随机均分为两组(n=40）。丙泊酚组（P组）、依托咪酯和丙泊酚混合液组（EP组）。先给予舒芬太尼0.1μg/kg缓慢静注，P组静注丙泊酚（1 mL/3s）直至患者入睡（睫毛反射消失）开始手术，EP组静注依托咪酯脂肪乳与丙泊酚1∶1混合液（1 mL/3 s）(依托咪酯脂肪乳与丙泊酚按体积1∶1混合，含依托咪酯1 mg/mL及丙泊酚5 mg/mL）直至患者入睡（睫毛反射消失）开始手术，视手术时间及患者体动情况酌情追加药物2~3 mL，两组患者术中均予鼻导管持续吸氧(3 L/min)，术中观察血压、心率、呼吸、SpO2、麻醉效果Aldrete改良评分、到达符合离院标准的时间及满意度、眩晕、恶心呕吐、肌阵挛、注射痛、术中知晓及麻醉效果。结果两组血压、心率、呼吸、SpO2、麻醉效果Aldrete改良评分、到达符合离院标准的时间及满意度、眩晕、恶心呕吐、肌阵挛、注射痛、术中知晓及麻醉效果差异明显。结论依托咪酯和丙泊酚混合液麻醉一种是更有效、更安全、且不良反应少的无痛人流麻醉方法。
目的：觀察依託咪酯和丙泊酚混閤液在無痛人流中的痳醉效果。方法選擇門診ASAⅠ~Ⅱ級自願接受無痛人工流產手術的患者80例，隨機均分為兩組(n=40）。丙泊酚組（P組）、依託咪酯和丙泊酚混閤液組（EP組）。先給予舒芬太尼0.1μg/kg緩慢靜註，P組靜註丙泊酚（1 mL/3s）直至患者入睡（睫毛反射消失）開始手術，EP組靜註依託咪酯脂肪乳與丙泊酚1∶1混閤液（1 mL/3 s）(依託咪酯脂肪乳與丙泊酚按體積1∶1混閤，含依託咪酯1 mg/mL及丙泊酚5 mg/mL）直至患者入睡（睫毛反射消失）開始手術，視手術時間及患者體動情況酌情追加藥物2~3 mL，兩組患者術中均予鼻導管持續吸氧(3 L/min)，術中觀察血壓、心率、呼吸、SpO2、痳醉效果Aldrete改良評分、到達符閤離院標準的時間及滿意度、眩暈、噁心嘔吐、肌陣攣、註射痛、術中知曉及痳醉效果。結果兩組血壓、心率、呼吸、SpO2、痳醉效果Aldrete改良評分、到達符閤離院標準的時間及滿意度、眩暈、噁心嘔吐、肌陣攣、註射痛、術中知曉及痳醉效果差異明顯。結論依託咪酯和丙泊酚混閤液痳醉一種是更有效、更安全、且不良反應少的無痛人流痳醉方法。
목적：관찰의탁미지화병박분혼합액재무통인류중적마취효과。방법선택문진ASAⅠ~Ⅱ급자원접수무통인공유산수술적환자80례，수궤균분위량조(n=40）。병박분조（P조）、의탁미지화병박분혼합액조（EP조）。선급여서분태니0.1μg/kg완만정주，P조정주병박분（1 mL/3s）직지환자입수（첩모반사소실）개시수술，EP조정주의탁미지지방유여병박분1∶1혼합액（1 mL/3 s）(의탁미지지방유여병박분안체적1∶1혼합，함의탁미지1 mg/mL급병박분5 mg/mL）직지환자입수（첩모반사소실）개시수술，시수술시간급환자체동정황작정추가약물2~3 mL，량조환자술중균여비도관지속흡양(3 L/min)，술중관찰혈압、심솔、호흡、SpO2、마취효과Aldrete개량평분、도체부합리원표준적시간급만의도、현훈、악심구토、기진련、주사통、술중지효급마취효과。결과량조혈압、심솔、호흡、SpO2、마취효과Aldrete개량평분、도체부합리원표준적시간급만의도、현훈、악심구토、기진련、주사통、술중지효급마취효과차이명현。결론의탁미지화병박분혼합액마취일충시경유효、경안전、차불량반응소적무통인류마취방법。
Objective To observe the anesthetic effect of etomidate and propofol mixture in painless artiifcial abortion. Methods The clinic ASAⅠ-Ⅱvoluntarily accept the operation of painless artiifcial abortion in 80 cases,were randomly averagely divided into two groups (n=40). Propofol group (group P),etomidate and propofol mixture group (group EP),give ifrst sulfentanil 0.1μg/kg slowly intravenous injection. Group P intravenous infusion of propofol (1 mL/3s) patients with sleep (until loss of eyelash relfex) began operation;group EP propofol and etomidate fat emulsion injection static 1∶1 mixture (1 mL/3s) (propofol and etomidate fat emulsion by volume 1∶1 mixed with 1 mg/mL etomidate and 5 mg/mL of propofol) until the patients to sleep (loss of eyelash relfex) began operation,as the operation time and patient movement where appropriate,additional drugs 2-3mL,patients in the two groups were given nasal catheter oxygen (3 L/min),to observe intraoperative blood pressure,heart rate,respiration,SpO2,anesthesia effect in Aldrete modiifed score,to meet the awareness,anesthetic effect,standard discharging time and satisfaction,dizziness,nausea and vomiting,myoclonus,injection pain. Results Two groups of blood pressure,heart rate,respiration,SpO2,anesthesia effect in Aldrete modiifed score,standard discharging time and satisfaction,dizziness,nausea and vomiting,m yoclonus,injection pain,awareness during operation and anesthesia effect are different. Conclusion Etomidate and propofol mixture anesthesia is a better anesthesia method for painless more effective,safer,and less side effects.
