中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2014年
30期
40-41
,共2页
参芪十一味颗粒%直肠癌术后%FOLFOX-4方案
參芪十一味顆粒%直腸癌術後%FOLFOX-4方案
삼기십일미과립%직장암술후%FOLFOX-4방안
Shenqishiyiwei Granule%Rectal cancer of postoperative%FOLFOX-4 chemotherapeutic protocol
目的：观察参芪十一味颗粒在辅助直肠癌术后FOLFOX-4方案化疗中的临床疗效。方法73例直肠癌术后患者均采用FOLFOX-4方案化疗，其中治疗组34例患者化疗前1周开始加用参芪十一味颗粒。观察两组化疗后生活质量及血液毒性反应变化情况。结果化疗4周期、6周期后患者生活质量评价治疗组优于对照组（P<0.05）。此外，治疗组化疗后血液毒性反应明显低于对照组，差异有显著性（P<0.05）。结论参芪十一味颗粒对直肠癌术后FOLFOX-4方案化疗有一定减毒作用。
目的：觀察參芪十一味顆粒在輔助直腸癌術後FOLFOX-4方案化療中的臨床療效。方法73例直腸癌術後患者均採用FOLFOX-4方案化療，其中治療組34例患者化療前1週開始加用參芪十一味顆粒。觀察兩組化療後生活質量及血液毒性反應變化情況。結果化療4週期、6週期後患者生活質量評價治療組優于對照組（P<0.05）。此外，治療組化療後血液毒性反應明顯低于對照組，差異有顯著性（P<0.05）。結論參芪十一味顆粒對直腸癌術後FOLFOX-4方案化療有一定減毒作用。
목적：관찰삼기십일미과립재보조직장암술후FOLFOX-4방안화료중적림상료효。방법73례직장암술후환자균채용FOLFOX-4방안화료，기중치료조34례환자화료전1주개시가용삼기십일미과립。관찰량조화료후생활질량급혈액독성반응변화정황。결과화료4주기、6주기후환자생활질량평개치료조우우대조조（P<0.05）。차외，치료조화료후혈액독성반응명현저우대조조，차이유현저성（P<0.05）。결론삼기십일미과립대직장암술후FOLFOX-4방안화료유일정감독작용。
Objective?To?observe?the?clinical?effect?of?Shenqishiyiwei?Granule?for?assistance?of?chemotherapy?with?FOLFOX-4?chemotherapeutic?protocol?in?treating?rectal?cancer?of?postoperative.?Methods?Seventy?three?patients?with?rectal?cancer?of?postoperative?were?treated?with?FOLFOX-4?chemotherapeutic?protocol,?to?the?thirty-four?patients?in?the?treated?group?among?them,?additional?medication?of?Shenqishiyiwei?Granule?was?started?one?week?before?the?beginning of chemotherapy. The changes on quality of life(QOL)and hematological toxicity of therapy were observed. Results?After?four?or?six?circles?the?QOL of the treated group was better than that of the control(P<0.05).The?hematological?toxicity?in?the?treated?group?was?lower?than?that?in?the?control?group?showing signiifcant difference(P<0.05).?Conclusion?Shenqishiyiwei Granule has deifnite toxicity relieving effect on chemotherapy in treating rectal cancer of?postoperative.
