CAJ | 학술논문

目的：探讨食管癌术后早期肠内营养(EN)的临床应用效果。方法将42例手术治疗的食管癌患者随机分为EN组和全肠外营养（TPN）组，观察比较二者患者手术前后营养状况、手术后恢复情况及并发症发生情况。结果手术后7 d，EN组清蛋白、前清蛋白明显高于TPN组，比较有统计学差异（P均＜0.05），而体质量和血红蛋白指标在两组之间比较无统计学差异（P均＞0.05）。术后，与TPN组相比，EN组肛门排气时间和排便时间明显缩短，比较都有统计学意义（P均＜0.05）。术后并发症方面，EN的并发症发生率为9.5%，明显低于TPN组38.1%的并发症发生率（P＜0.05）。结论食管癌术后患者早期应用EN的临床效果良好，可以改善患者的营养状况，促进术后胃肠功能恢复，且并发症发生少，明显优于TPN，值得临床上进一步研究。
목적：탐토식관암술후조기장내영양(EN)적림상응용효과。방법장42례수술치료적식관암환자수궤분위EN조화전장외영양（TPN）조，관찰비교이자환자수술전후영양상황、수술후회복정황급병발증발생정황。결과수술후7 d，EN조청단백、전청단백명현고우TPN조，비교유통계학차이（P균＜0.05），이체질량화혈홍단백지표재량조지간비교무통계학차이（P균＞0.05）。술후，여TPN조상비，EN조항문배기시간화배편시간명현축단，비교도유통계학의의（P균＜0.05）。술후병발증방면，EN적병발증발생솔위9.5%，명현저우TPN조38.1%적병발증발생솔（P＜0.05）。결론식관암술후환자조기응용EN적림상효과량호，가이개선환자적영양상황，촉진술후위장공능회복，차병발증발생소，명현우우TPN，치득림상상진일보연구。
Objective To investigate the clinical effect of early enteral nutrition (EN) in postoperative patients with esophageal cancer. Methods 42 cases of postoperative patients with esophageal caner were randomLy divided into EN group (n=21) and total parenteral nutrition (TPN) group (n=21). Then, nutritional status, general recovery and occurrence rate of complications between the two groups were compared. Results Seven days after the operation, albumin and prealbumin in the EN group were statistically higher than those in the TPN group (both P<0.05), while body weight and hemoglobin in the two groups were statistically same (both P>0.05). In comparison to the TPN group, the time needed for recovery of anal exsuflfation and defecation in the EN group were statistically shorter (both P<0.05). As to complications, the occurrence rate in the EN group was 9.5%, which was statistically lower than that of 38.1%in the TPN group (P<0.05). Conclusion Clinical effect of early EN in postoperative patients with esophageal caner was reliable, which could improve patients’ nutritional status, promote recovery of gastrointestinal function and reduce occurrence rate of complications, with more signiifcant advantages than those of TPN.