中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2014年
29期
29-30,31
,共3页
降钙素原%社区获得性肺炎%抗生素%老年
降鈣素原%社區穫得性肺炎%抗生素%老年
강개소원%사구획득성폐염%항생소%노년
Procalcitonin%Community-acquired pneumonia%Antibiotic%Elderly
目的：探讨血清降钙素原(procalcitonin，PCT)对接受门诊治疗的老年非重症社区获得性肺炎（community-acquired pneumonia）患者的抗生素使用指导意义。方法选择接受门诊治疗的老年非重症CAP患者55例，分为PCT监测组28例，对照组27例。入组患者均监测血清PCT水平，对照组根据我国CAP治疗指南选择抗生素治疗方案；PCT组在血清PCT≥0.25μg/L时使用抗生素治疗，PCT＜0.25μg/L时不予抗生素治疗，复诊时亦按照此标准决定是否继续使用抗生素。比较上述两组治疗两周后临床指标、治疗费用、抗生素使用时间及分布的差异。结果两组治疗后各临床指标的恢复无明显差异（P＞0.05），PCT组抗生素使用时间低于对照组（P＜0.05），抗生素使用分布上明显优于对照组（P＜0.05），同时治疗费用也低于对照组（P＜0.05）。结论老年非重症CAP患者可以依据PCT水平指导抗生素应用，能够缩短抗生素疗程，降低治疗费用。
目的：探討血清降鈣素原(procalcitonin，PCT)對接受門診治療的老年非重癥社區穫得性肺炎（community-acquired pneumonia）患者的抗生素使用指導意義。方法選擇接受門診治療的老年非重癥CAP患者55例，分為PCT鑑測組28例，對照組27例。入組患者均鑑測血清PCT水平，對照組根據我國CAP治療指南選擇抗生素治療方案；PCT組在血清PCT≥0.25μg/L時使用抗生素治療，PCT＜0.25μg/L時不予抗生素治療，複診時亦按照此標準決定是否繼續使用抗生素。比較上述兩組治療兩週後臨床指標、治療費用、抗生素使用時間及分佈的差異。結果兩組治療後各臨床指標的恢複無明顯差異（P＞0.05），PCT組抗生素使用時間低于對照組（P＜0.05），抗生素使用分佈上明顯優于對照組（P＜0.05），同時治療費用也低于對照組（P＜0.05）。結論老年非重癥CAP患者可以依據PCT水平指導抗生素應用，能夠縮短抗生素療程，降低治療費用。
목적：탐토혈청강개소원(procalcitonin，PCT)대접수문진치료적노년비중증사구획득성폐염（community-acquired pneumonia）환자적항생소사용지도의의。방법선택접수문진치료적노년비중증CAP환자55례，분위PCT감측조28례，대조조27례。입조환자균감측혈청PCT수평，대조조근거아국CAP치료지남선택항생소치료방안；PCT조재혈청PCT≥0.25μg/L시사용항생소치료，PCT＜0.25μg/L시불여항생소치료，복진시역안조차표준결정시부계속사용항생소。비교상술량조치료량주후림상지표、치료비용、항생소사용시간급분포적차이。결과량조치료후각림상지표적회복무명현차이（P＞0.05），PCT조항생소사용시간저우대조조（P＜0.05），항생소사용분포상명현우우대조조（P＜0.05），동시치료비용야저우대조조（P＜0.05）。결론노년비중증CAP환자가이의거PCT수평지도항생소응용，능구축단항생소료정，강저치료비용。
Objective To evaluate the value of serum procaleitonin(PCT) on antibiotic treatment of elderly non severe community-acquired pneumonia(CAP). Methods 55 patients with non severe CAP in outpatient were randomly assigned into two groups:PCT group (n=28) and control group (n=27). Serum PCT levels of al patients were measured before study admission. On the base of similarly normal treatment, the control group received antibiotics according to the at ending physicians and the PCT group were treated with antibiotics according to serum PCT levels. Antibiotic treatment was applied with PCT≥0.25μg/L and was discouraged with PCT<0.25μg/L. Subsequent visit also according to the standard to decide whether to continue to use antibiotics. Compare clinical indicators, the cost of treatment, the antibiotic use time and the distribution of the difference after two weeks treatment. Results The level of PCT in the PCT group was lower than treatment before;rates of antibiotics use was lower than that of the control group. There was no signiifcant difference in the prognosis of patients. Conclusion PCT could be used in antibiotic treatment of elderly non severe CAP in outpatient, which may reduce antibiotic use, shorten antibiotic duration and lower costs of antibiotic.
