浙江中医药大学学报
浙江中醫藥大學學報
절강중의약대학학보
JOURNAL OF ZHEJIANG UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
2014年
10期
1159-1162
,共4页
功能性消化不良%数据挖掘%证治规律%医案%王坤根
功能性消化不良%數據挖掘%證治規律%醫案%王坤根
공능성소화불량%수거알굴%증치규률%의안%왕곤근
functional dyspepsia%data mining%therapeutic principles%medical records%Wang Kungen
[目的]利用数据挖掘技术探讨王坤根教授诊治功能性消化不良（FD）的证治规律。[方法]建立王坤根教授2008年8月至2013年12月的门诊医案数据库，对数据规范化处理后进行频数分析、关联规则分析等数据挖掘研究。[结果]符合纳入、排除标准医案共408则，餐后不适综合征是老年组FD患者的主要亚型，上腹痛综合征是非老年组FD患者的主要亚型。王坤根教授FD医案中主要证型依次是：肝气犯胃证、脾虚气滞证、胃气不和证、气滞湿阻证、痰热内扰证。主要方剂依次是：二陈汤、左金丸、四君子汤、四逆散、六君子汤、香苏饮、温胆汤。方证间肝气犯胃证与四逆散、左金丸，脾虚气滞证与四君子汤、二陈汤，胃气不和证与香苏饮、二陈汤，气滞湿阻证与二陈汤、平胃散，痰热内扰证与温胆汤、二陈汤存在较强的关联性。药对间制半夏与陈皮、制半夏与茯苓、黄连与淡吴萸、枳壳与川朴、柴胡与白芍、茯苓与白术、陈皮与苏梗、茯苓与党参、柴胡与郁金存在较强的关联性。[结论]老年组与非老年组FD的发病率及亚型分布存在一定差异；疏肝和胃法、疏肝解郁法、和胃降逆法、行气化湿法、清化痰热法是王坤根教授治疗FD的主要治则。
[目的]利用數據挖掘技術探討王坤根教授診治功能性消化不良（FD）的證治規律。[方法]建立王坤根教授2008年8月至2013年12月的門診醫案數據庫，對數據規範化處理後進行頻數分析、關聯規則分析等數據挖掘研究。[結果]符閤納入、排除標準醫案共408則，餐後不適綜閤徵是老年組FD患者的主要亞型，上腹痛綜閤徵是非老年組FD患者的主要亞型。王坤根教授FD醫案中主要證型依次是：肝氣犯胃證、脾虛氣滯證、胃氣不和證、氣滯濕阻證、痰熱內擾證。主要方劑依次是：二陳湯、左金汍、四君子湯、四逆散、六君子湯、香囌飲、溫膽湯。方證間肝氣犯胃證與四逆散、左金汍，脾虛氣滯證與四君子湯、二陳湯，胃氣不和證與香囌飲、二陳湯，氣滯濕阻證與二陳湯、平胃散，痰熱內擾證與溫膽湯、二陳湯存在較彊的關聯性。藥對間製半夏與陳皮、製半夏與茯苓、黃連與淡吳萸、枳殼與川樸、柴鬍與白芍、茯苓與白術、陳皮與囌梗、茯苓與黨參、柴鬍與鬱金存在較彊的關聯性。[結論]老年組與非老年組FD的髮病率及亞型分佈存在一定差異；疏肝和胃法、疏肝解鬱法、和胃降逆法、行氣化濕法、清化痰熱法是王坤根教授治療FD的主要治則。
[목적]이용수거알굴기술탐토왕곤근교수진치공능성소화불량（FD）적증치규률。[방법]건립왕곤근교수2008년8월지2013년12월적문진의안수거고，대수거규범화처리후진행빈수분석、관련규칙분석등수거알굴연구。[결과]부합납입、배제표준의안공408칙，찬후불괄종합정시노년조FD환자적주요아형，상복통종합정시비노년조FD환자적주요아형。왕곤근교수FD의안중주요증형의차시：간기범위증、비허기체증、위기불화증、기체습조증、담열내우증。주요방제의차시：이진탕、좌금환、사군자탕、사역산、륙군자탕、향소음、온담탕。방증간간기범위증여사역산、좌금환，비허기체증여사군자탕、이진탕，위기불화증여향소음、이진탕，기체습조증여이진탕、평위산，담열내우증여온담탕、이진탕존재교강적관련성。약대간제반하여진피、제반하여복령、황련여담오유、지각여천박、시호여백작、복령여백술、진피여소경、복령여당삼、시호여욱금존재교강적관련성。[결론]노년조여비노년조FD적발병솔급아형분포존재일정차이；소간화위법、소간해욱법、화위강역법、행기화습법、청화담열법시왕곤근교수치료FD적주요치칙。
Objective]To study Professor Wang Kungen's therapeutic principles in treating functional dyspepsia by data mining therapy. [Method]First, establish Wang Kungen's medical records database;then do data standardization and data mining.[Result]There are total y 408 cases that meet the demand. Postprandial distress syndrome is the major subtype of senile group while epigastric pain syndrome is the major subtype of non senile group. The major patterns of syndrome of FD in Professor Wang Kungen's medical records are as fol ows: liver qi attacking the stomach, deficiency and stagnation of spleen Qi, disharmony of stomach qi, stagnation of qi and accumulation of dampness, phlegm-heat harassing the inner body. The major prescriptions are as fol ows:ErChen Decoction, ZuoJin Pil s, SiJunZi Decoction, SiNi Powder, LiuJunZi Decoction, XiangSu Decoction, WenDan Decoction. There is close correlation between prescriptions and patterns as fol ows:liver qi attacking the stomach and SiNi Powder, ZuoJin Pil s;stagnation of qi and accumulation of dampness and ErChen Decoction,PingWei powder;phlegm-heat harassing the inner body and WenDan Decoction, ErChen Decoction; There is close correlation between herbs as fol ows: Processed Rhizoma Pinel iae and Tangerine Peel, Processed Rhizoma Pinel iae and Poria cocos; Rhizoma Coptidis and Processed Evodia rutaecarpa; Fructus Aurantii and Processed Mangnolia officinalis; Radix Bupleuri and Radix Paeoniae Alba; Poria cocos and Atractylodes;Tangerine Peel and Caulis Peril ae; Poria cocos and Codonopsis pilosula; Radix Bupleuri and Curcuma aromatica. [Conclusion]The incidence and subtype of FD between female group and male group is different. Professor Wang Kungen's therapeutic principles in treating FD are clearing liver and adjusting stomach, soothing liver-qi stagnation,harmonizing stomach and lowering adverse qi, promoting the circulation of qi and resolving dampness and clearing phlegm heat.
