CAJ | 학술논문

目的：探讨卵巢Brenner瘤的诊断及治疗方法。方法：回顾性分析自2001年1月至2013年12月间温州医科大学附属第二医院妇科收治的29例卵巢Brenner瘤患者的临床资料，并对其进行随访，总结、分析其诊治特点。结果：29例患者术前多无特异性症状，大部分（19例）因B超检查发现附件或盆腔包块就诊，所有患者均经手术病理证实，其中良性26例，交界性2例，恶性1例；单侧20例，双侧9例；单纯性的卵巢Brenner瘤14例，合并其他卵巢肿瘤或子宫肿瘤15例；手术行肿瘤剥除5例，行单侧附件切除10例，行双侧附件切除术8例，行全子宫双附件切除术5例，行全子宫双附件切除及盆腹腔淋巴结清扫全面分期手术1例。术后随访：失访1例；行肿瘤剥除者复发1例；恶性患者术后化疗6个疗程，随访2年，现健在；因其他原因死亡2例。结论：卵巢Brenner瘤大多数为良性，其临床表现、相关检查及治疗方案与卵巢上皮性肿瘤无异质性，临床上以术后病理回报确诊，手术治疗临床疗效确切。
목적：탐토란소Brenner류적진단급치료방법。방법：회고성분석자2001년1월지2013년12월간온주의과대학부속제이의원부과수치적29례란소Brenner류환자적림상자료，병대기진행수방，총결、분석기진치특점。결과：29례환자술전다무특이성증상，대부분（19례）인B초검사발현부건혹분강포괴취진，소유환자균경수술병리증실，기중량성26례，교계성2례，악성1례；단측20례，쌍측9례；단순성적란소Brenner류14례，합병기타란소종류혹자궁종류15례；수술행종류박제5례，행단측부건절제10례，행쌍측부건절제술8례，행전자궁쌍부건절제술5례，행전자궁쌍부건절제급분복강림파결청소전면분기수술1례。술후수방：실방1례；행종류박제자복발1례；악성환자술후화료6개료정，수방2년，현건재；인기타원인사망2례。결론：란소Brenner류대다수위량성，기림상표현、상관검사급치료방안여란소상피성종류무이질성，림상상이술후병리회보학진，수술치료림상료효학절。
Objective: To explore the diagnosis and treatment of ovarian Brenner tumor.Methods: The clinical data of 29 patients diagnosed as ovarian Brenner tumors were collected to retrospective analysis. The patients were treated in Gynecology department of the Second Afifliated Hospital of Wenzhou Medical Univer-sity from January 2001 to December 2013, and the follow-up visit data was surveyed. The results we collected about the characteristics of diagnosis and treatment of ovarian Brenner tumor were summarized and analyzed. Results: In our 29 cases, most of patients were asymptomatic in the preoperative period. Nineteen cases showed an incidentally asymptomatic adnexal mass in the annual gynecological ultrasound exam. It was conifrmed that, 2 cases and 1 case of patients were benign, borderline malignant tumor respectively by surgery in 26 cases. The tumor was unilateral in 20 cases and bilateral in 9 cases. Fourteen cases were pure Brenner tumors and 15 cases were mixed tumors consisting of a Brenner tumor element and other ovarian tumor or uterine neoplasms. In these cases, 5 cases performed an operation of tumor resection, 10 cases of unilateral salpingo-oophorectomy, 8 cases of bilateral adnexactomy, 5 cases of whole uterus double appendix resection, 1 case of radical hysterectomy ,bi-lateral salphing-oopherectomy and pelvic and para-aortic lymphadenectomy. During follow-up visits for 2 years, one recurrence occurred in tumor resection, 2 cases of patients died of other reasons, and 6 cases with malignant tumor have been alive after chemotherapy postoperatively up to now, excepted the losted one.Conclusion:Our results indicate that most of ovarian Brenner tumor will be benign with its clinical manifestations, relevant exami-nation and treatment have less differences with other ovarian epithelial tumor. Currently, the diagnosis of Brenner tumor is conifrmed clinically by postoperative pathology return, and the surgical treatment is effective.