实用肝脏病杂志
實用肝髒病雜誌
실용간장병잡지
JOURNAL OF CLINICAL HEPATOLOGY
2014年
6期
669-671,672
,共4页
周新人(综述)%王方(审校)
週新人(綜述)%王方(審校)
주신인(종술)%왕방(심교)
肝硬化%补体异常%进展
肝硬化%補體異常%進展
간경화%보체이상%진전
Cirrhosis%Complements%Progress
免疫炎症损伤在肝炎、肝硬化的发生发展中扮演了重要角色。目前,许多免疫炎症因子及补体成分已成为肝病发病机制研究的热点之一。补体异常与各种导致肝硬化的常见病因,如病毒性肝炎、自身免疫性肝病、酒精性肝病等均密切相关,同时还参与了肝硬化各种并发症的发生和发展。
免疫炎癥損傷在肝炎、肝硬化的髮生髮展中扮縯瞭重要角色。目前,許多免疫炎癥因子及補體成分已成為肝病髮病機製研究的熱點之一。補體異常與各種導緻肝硬化的常見病因,如病毒性肝炎、自身免疫性肝病、酒精性肝病等均密切相關,同時還參與瞭肝硬化各種併髮癥的髮生和髮展。
면역염증손상재간염、간경화적발생발전중분연료중요각색。목전,허다면역염증인자급보체성분이성위간병발병궤제연구적열점지일。보체이상여각충도치간경화적상견병인,여병독성간염、자신면역성간병、주정성간병등균밀절상관,동시환삼여료간경화각충병발증적발생화발전。
Immune disturbance plays an important roles in the pathogenesis and development of viral hepatitis and liver cirrhosis. Many inflammatory cytokines and complement components have become highlights in this field. Abnormal complement balance has been found in many liver diseases,such as viral hepatitis, autoimmune liver disease,alcoholic liver disease and so on. We discuss some hotspots in this review.