医学影像学杂志
醫學影像學雜誌
의학영상학잡지
JOURNAL OF MEDICAL IMAGING
2014年
10期
1712-1715
,共4页
冯菲%余仲飞%张建%杨剑%胡胜平%孙高峰%程超%董爱生%孔令山%左长京
馮菲%餘仲飛%張建%楊劍%鬍勝平%孫高峰%程超%董愛生%孔令山%左長京
풍비%여중비%장건%양검%호성평%손고봉%정초%동애생%공령산%좌장경
IgG4相关性疾病%体层摄影术, 发射型计算机%体层摄影术, X线计算机%脱氧葡萄糖
IgG4相關性疾病%體層攝影術, 髮射型計算機%體層攝影術, X線計算機%脫氧葡萄糖
IgG4상관성질병%체층섭영술, 발사형계산궤%체층섭영술, X선계산궤%탈양포도당
IgG4 related diseases(IgG4RD)%Tomography%Emission-computed%Tomography,X-ray computed%Deox-yglucose
目的：分析IgG4相关性疾病（IgG4 related disease ，IgG4RD）全身PET/CT 表现特点，提高对该病的认识及诊断，指导临床诊治。方法回顾性分析14例IgG4相关性疾病患者（男性12例，女性2例，年龄43～75岁，中位年龄59岁的18 F-FDG全身PET/CT图像资料，分析受累脏器的形态、密度和18 F-FDG葡萄糖代谢改变。结果14例患者血清IgG4水平均增高，（970．14±950．70）mg/dl（136～3690mg/dl），18 F-FDG全身PET/CT显像显示IgG4RD患者多个脏器受累：12例（85．7％）胰腺受累，表现为胰腺弥漫性或阶段性肿大，FDG摄取增高；9例（62．3％）唾液腺受累，表现为单侧或双侧唾液腺饱满、肿大，FDG摄取增高；6例（42．9％）胆管系统受累，表现为肝内外胆管轻度扩张，管壁轻度增厚，沿胆管FDG索条样摄取增高；12例男性患者中7例（58．3％）前列腺受累，表现为前列腺单侧叶或双侧叶 FDG摄取增高；另还可见甲状腺（5例）、肺部（4例）、肠道（4例）、大动脉（2例）、肾脏（1例）受累改变。结论 IgG4RD是一种全身性、系统性的疾病，18 F-FDG PET/CT很好地显示了IgG4RD全身器官受累的形态和代谢改变，有利于IgG4RD的诊断和全身评估。
目的：分析IgG4相關性疾病（IgG4 related disease ，IgG4RD）全身PET/CT 錶現特點，提高對該病的認識及診斷，指導臨床診治。方法迴顧性分析14例IgG4相關性疾病患者（男性12例，女性2例，年齡43～75歲，中位年齡59歲的18 F-FDG全身PET/CT圖像資料，分析受纍髒器的形態、密度和18 F-FDG葡萄糖代謝改變。結果14例患者血清IgG4水平均增高，（970．14±950．70）mg/dl（136～3690mg/dl），18 F-FDG全身PET/CT顯像顯示IgG4RD患者多箇髒器受纍：12例（85．7％）胰腺受纍，錶現為胰腺瀰漫性或階段性腫大，FDG攝取增高；9例（62．3％）唾液腺受纍，錶現為單側或雙側唾液腺飽滿、腫大，FDG攝取增高；6例（42．9％）膽管繫統受纍，錶現為肝內外膽管輕度擴張，管壁輕度增厚，沿膽管FDG索條樣攝取增高；12例男性患者中7例（58．3％）前列腺受纍，錶現為前列腺單側葉或雙側葉 FDG攝取增高；另還可見甲狀腺（5例）、肺部（4例）、腸道（4例）、大動脈（2例）、腎髒（1例）受纍改變。結論 IgG4RD是一種全身性、繫統性的疾病，18 F-FDG PET/CT很好地顯示瞭IgG4RD全身器官受纍的形態和代謝改變，有利于IgG4RD的診斷和全身評估。
목적：분석IgG4상관성질병（IgG4 related disease ，IgG4RD）전신PET/CT 표현특점，제고대해병적인식급진단，지도림상진치。방법회고성분석14례IgG4상관성질병환자（남성12례，녀성2례，년령43～75세，중위년령59세적18 F-FDG전신PET/CT도상자료，분석수루장기적형태、밀도화18 F-FDG포도당대사개변。결과14례환자혈청IgG4수평균증고，（970．14±950．70）mg/dl（136～3690mg/dl），18 F-FDG전신PET/CT현상현시IgG4RD환자다개장기수루：12례（85．7％）이선수루，표현위이선미만성혹계단성종대，FDG섭취증고；9례（62．3％）타액선수루，표현위단측혹쌍측타액선포만、종대，FDG섭취증고；6례（42．9％）담관계통수루，표현위간내외담관경도확장，관벽경도증후，연담관FDG색조양섭취증고；12례남성환자중7례（58．3％）전렬선수루，표현위전렬선단측협혹쌍측협 FDG섭취증고；령환가견갑상선（5례）、폐부（4례）、장도（4례）、대동맥（2례）、신장（1례）수루개변。결론 IgG4RD시일충전신성、계통성적질병，18 F-FDG PET/CT흔호지현시료IgG4RD전신기관수루적형태화대사개변，유리우IgG4RD적진단화전신평고。
Objective To analyze the PET/CT imaging characteristics of IgG4 related diseases (IgG4 related diseases , IgG4RD) and to investigate the function of 18 F-FDG PET/CT in diagnosing of IgG4RD and whole-body evaluation .Meth-ods Whole-body 18 F-FDG PET /CT findings in 14 patients (male 12 ,female 2 ,age from 43 to 75 ,the median age of 59 years old) with clinical conformed IgG4RD were reviewed retrospectively .Organs'morphology changes ,density alter and 18 F-FDG metabolism were observed .Results All of 14 cases had a high level of serum IgG4 ,(970 .14 ± 950 .70) mg/dl (136~3690) mg/dl .18 F-FDG PET/CT imaging showed that there were multiple organ involvement in IgG4RD and 12 ca-ses (85 .7% ) with pancreas involvement ,which were characterized by diffuse or segmental enlargement of the pancreas with increased 18 F-FDG uptake;9 cases (62 .3% ) with salivary gland involvement were characterized by unilateral or bilat-eral salivary glands swelling with increased 18 F-FDG uptake;6 cases (42 .9% ) had bile duct system involved ,which were characterized by mild expansion of bile ducts with mild thickening wall .Along the bile duct ,18 F-FDG uptake was in-creased;7 in 12 male patients (58 .3% ) had prostatic involved characterized by unilateral or bilateral lobe with increased 18 F-FDG uptake;Other organs were involved ,including thyroid (5 cases) ,lung (4 cases) ,intestine (4 cases) ,artery (2 cases) and kidney (1 case) .Conclusion IgG4RD is a systemic disease .18 F-FDG PET/CT shows well the changes and metabolic characteristics of organs ,which are involved in IgG4RD .It plays a distinct role in diagnosis of IgG4RD and w hole-body evaluation .
