CAJ | 학술논문

目的：比较阿尔茨海默病(AD)与血管性痴呆(VD)头颅磁共振成像(MRI)和脑电图特征。方法观察39例AD患者、56例VD患者的头颅MRI和脑电图资料。MRI比较大脑萎缩、海马萎缩、脑白质疏松症的比例；脑电图比较轻度异常和中重度异常的比例，进行功率谱分析。结果与VD患者相比，AD患者大脑萎缩、海马萎缩的发生率较高，脑白质疏松症发生率较低。AD患者脑电图中重度异常的较多，(θ+δ)/(α+β)比值增高(P<0.05)。结论单纯大脑萎缩而缺乏脑白质疏松症和缺血灶的痴呆患者应高度怀疑AD，脑电图出现中重度异常则进一步支持AD的诊断。
목적：비교아이자해묵병(AD)여혈관성치태(VD)두로자공진성상(MRI)화뇌전도특정。방법관찰39례AD환자、56례VD환자적두로MRI화뇌전도자료。MRI비교대뇌위축、해마위축、뇌백질소송증적비례；뇌전도비교경도이상화중중도이상적비례，진행공솔보분석。결과여VD환자상비，AD환자대뇌위축、해마위축적발생솔교고，뇌백질소송증발생솔교저。AD환자뇌전도중중도이상적교다，(θ+δ)/(α+β)비치증고(P<0.05)。결론단순대뇌위축이결핍뇌백질소송증화결혈조적치태환자응고도부의AD，뇌전도출현중중도이상칙진일보지지AD적진단。
Objective To compare the features of magnetic resonance imaging (MRI) and electroencephalogram (EEG) to differentiate Alzheimer's disease (AD) and vascular dementia (VD). Methods It was analyzed of the MRI and EEG from 39 patients with AD and 56 pa-tients with VD, to compare the proportion of cerebral atrophy, hippocampal atrophy and leukoaraiosis in MRI, and the proportion of the moderate to severe disorder of EEG and the power spectrum. Results The proportion of cerebral atrophy and hippocampal atrophy was more and leukoaraiosis was less in the AD group than those in the VD group. The proportion of the moderate to severe disorder of EEG increased in AD group, and the ratio of (θ+δ)/(α+β) of whole brain was more in the AD group than in the VD group (P<0.05). Conclusion It is more likely to be AD in dementia patients with atrophy without leukoaraiosis and cerebral ischemic lesions, especially for those with severe abnor-mal EEG.