CAJ | 학술논문

目的：探讨氨茶碱与多索茶碱治疗支气管哮喘急性发作临床效果差异。方法选择我院80例支气管急性发作患者，随机分为观察组和对照组。两组均给予常规治疗，对照组给予氨茶碱，观察组给予多索茶碱。观察两组患者肺功能改善情况，评定治疗效果，观察不良反应发生情况。结果观察组治疗后的FEV1、PEF、FEV1/FVC和对照组治疗后的FEV1、PEF、FEV1/FVC比较，差异有统计学意义（P＜0.05）。观察组显效率和有效率之和高于对照组，差异有统计学意义（P＜0.05）。观察组不良反应发生率低于对照组，差异有统计学意义（P＜0.05）。结论多索茶碱治疗支气管哮喘急性发作效果显著，其临床效果优于氨茶碱，值得借鉴。
목적：탐토안다감여다색다감치료지기관효천급성발작림상효과차이。방법선택아원80례지기관급성발작환자，수궤분위관찰조화대조조。량조균급여상규치료，대조조급여안다감，관찰조급여다색다감。관찰량조환자폐공능개선정황，평정치료효과，관찰불량반응발생정황。결과관찰조치료후적FEV1、PEF、FEV1/FVC화대조조치료후적FEV1、PEF、FEV1/FVC비교，차이유통계학의의（P＜0.05）。관찰조현효솔화유효솔지화고우대조조，차이유통계학의의（P＜0.05）。관찰조불량반응발생솔저우대조조，차이유통계학의의（P＜0.05）。결론다색다감치료지기관효천급성발작효과현저，기림상효과우우안다감，치득차감。
Objective Toexplore the effect comparison of Aminophylline and doxofylline on acute attack of bronchial asthma clinical. Methods 80 cases with acute episode of bronchial were selected and randomly divided into observation group and control group. The two groups were given conventional therapy, the control group were given aminophylline, the observation group was given doxofylline. The pulmonary function improvement, the therapeutic effect, the adverse events were observed in two groups. Results The FEV1, PEF, FEV1/FVC in the observation after treatment compared with those in the control group after treatment, the difference was statistically significant(P<0.05). The significant efficiency and efficiency in the observation group was higher than that in the control group, the difference was statistically significant (P<0.05). The adverse reaction in observation group was higher than that in the control group, the difference was statistically significant (P<0.05). Conclusion Doxofylline on acute attack of bronchial asthma effect is remarkable, and the clinical effect is better than that of aminophylline.