天津医药
天津醫藥
천진의약
TIANJIN MEDICAL JOURNAL
2014年
11期
1138-1140,1141
,共4页
Apelin-13%心血管系统%呼吸系统%神经系统%内分泌系统
Apelin-13%心血管繫統%呼吸繫統%神經繫統%內分泌繫統
Apelin-13%심혈관계통%호흡계통%신경계통%내분비계통
Apelin-13%cardiovascular system%respiratory system%central nervous system%endocrine system
Apelin是由77个氨基酸构成的多肽,其受体为血管紧张素样G蛋白偶联受体(APJ)。Apelin/APJ系统在外周与中枢均有广泛分布;Apelin-13是Apelin亚型之一,具有较强的生物活性。本文综述了Apelin-13参与心血管系统、呼吸系统、神经系统、消化系统和内分泌系统等生理病理过程调节的研究新进展。
Apelin是由77箇氨基痠構成的多肽,其受體為血管緊張素樣G蛋白偶聯受體(APJ)。Apelin/APJ繫統在外週與中樞均有廣汎分佈;Apelin-13是Apelin亞型之一,具有較彊的生物活性。本文綜述瞭Apelin-13參與心血管繫統、呼吸繫統、神經繫統、消化繫統和內分泌繫統等生理病理過程調節的研究新進展。
Apelin시유77개안기산구성적다태,기수체위혈관긴장소양G단백우련수체(APJ)。Apelin/APJ계통재외주여중추균유엄범분포;Apelin-13시Apelin아형지일,구유교강적생물활성。본문종술료Apelin-13삼여심혈관계통、호흡계통、신경계통、소화계통화내분비계통등생리병리과정조절적연구신진전。
Apelin is a polypeptide consisting of 77 amino acids. Apelin receptors are found to be the angiotensin-like G protein coupled receptor (APJ). Apelin/APJ system is widely distributed in the peripheral and central nervous system. Apelin-13 is one of the subtypes of Apelin, which has strong biological activity. This study reviewed the new research prog?ress of Apelin-13 on physiological and pathological processes involved in the cardiovascular system, respiratory system, ner?vous system, digestive system and endocrine system.