CAJ | 학술논문

目的：了解嗜麦芽寡养单胞菌的临床分布及对抗菌药物的耐药性。方法采用 VITEK-2 COMPACT全自动微生物鉴定仪及纸片扩散（K-B）法对分离的63株嗜麦芽寡养单胞菌的来源分布、药物敏感性结果进行统计分析。结果63株嗜麦芽寡养单胞菌在临床标本中分布以痰液为主，占87．3％；感染主要发生在新生儿科为17．4％和胸外科17．4％；其次为呼吸科14．3％和重症监护病房（ICU）14．3％；嗜麦芽寡养单胞菌对亚胺培南耐药率为100．0％；而对左氧氟沙星、米诺环素、磺胺甲口恶唑-甲氧苄啶耐药率较低分别为1．6％、3．2％、3．2％。结论应加强对嗜麦芽寡养单胞菌耐药性监测，以指导临床根据药物敏感性试验结果合理选择抗菌药物。
목적：료해기맥아과양단포균적림상분포급대항균약물적내약성。방법채용 VITEK-2 COMPACT전자동미생물감정의급지편확산（K-B）법대분리적63주기맥아과양단포균적래원분포、약물민감성결과진행통계분석。결과63주기맥아과양단포균재림상표본중분포이담액위주，점87．3％；감염주요발생재신생인과위17．4％화흉외과17．4％；기차위호흡과14．3％화중증감호병방（ICU）14．3％；기맥아과양단포균대아알배남내약솔위100．0％；이대좌양불사성、미낙배소、광알갑구악서-갑양변정내약솔교저분별위1．6％、3．2％、3．2％。결론응가강대기맥아과양단포균내약성감측，이지도림상근거약물민감성시험결과합리선택항균약물。
Objective To investigate the clinical distribution and drug resistance of Stenotrophomonas maltophilia. Methods The clinical distribution and drug resistance analysis for 63 isolates of Stenotrophomonas maltophilia were performed by VITEK-2 COMPACT system and Kirby-Bauer (K-B)method.The results were analyzed statistically. Results The isolation rate was the highest in respiratory specimens .There was a highest isolation rate of 87.3%.The samples were mainly obtained from the wards of Neonatology Department (1 7.4%)and Thoracic Surgery(1 7.4%), followed by Respiratory Department (4.3%) and Intensive Care Unit (ICU ) (1 4.3%).The 63 isolates of Stenotrophomonas maltophilia were highly resistant to imipenem,and the resistance rate was 1 00.0%.The resistance rates to levofloxacin,minocyline and triethoprim-sulfamethoxazole were 1 .6%,3.2% and 3.2%.Conclusions It should enhance drug resistance monitoring of Stenotrophomonas maltophilia.Treatment based on drug susceptibility test should be adapted as soon as possible.