CAJ | 학술논문

目的：通过对 T1期高级别尿路上皮癌患者的术后随访,了解影响这类患者复发的因素。方法回顾性分析78例 T1期高级别尿路上皮癌患者,对其年龄、性别、肿瘤多发或单发、肿瘤大小、有无吸烟史等因素进行了χ2检验及多因素分析。结果78例患者术后复发率34.6%(27/78),术后2年内复发者19例。吸烟患者46例,均为男性,45.7%(21/46)出现术后复发。χ2检验示肿瘤大小(P =0.012)和吸烟史(P =0.014)对肿瘤复发的影响有统计学差异,多因素分析示肿瘤数目(P =0.027)、肿瘤大小(P =0.018)和吸烟史(P <0.001)有统计学差异。结论除了肿瘤数目、肿瘤大小是影响膀胱肿瘤患者预后的重要因素外,有吸烟史的 T1期高级别尿路上皮癌患者可能更容易复发。
목적：통과대 T1기고급별뇨로상피암환자적술후수방,료해영향저류환자복발적인소。방법회고성분석78례 T1기고급별뇨로상피암환자,대기년령、성별、종류다발혹단발、종류대소、유무흡연사등인소진행료χ2검험급다인소분석。결과78례환자술후복발솔34.6%(27/78),술후2년내복발자19례。흡연환자46례,균위남성,45.7%(21/46)출현술후복발。χ2검험시종류대소(P =0.012)화흡연사(P =0.014)대종류복발적영향유통계학차이,다인소분석시종류수목(P =0.027)、종류대소(P =0.018)화흡연사(P <0.001)유통계학차이。결론제료종류수목、종류대소시영향방광종류환자예후적중요인소외,유흡연사적 T1기고급별뇨로상피암환자가능경용역복발。
Objective To investigate the factors influencing the recurrence of patients with T1 high grade urothelial carcinoma by follow-up. Methods 78 cases of T1 high grade urothelial carci-noma patients were analysis retrospectively.Age,gender,tumor of multiple or single factors, tumor size,and smoking history were tested by χ2 test and multivariate analysis. Results 34.6%(27/78)patients was found recurrence after operative.1 9 cases recurred within 2 years after opera-tive.In 46 male patients with smoking history,45.7% (21/46)had postoperative recurrence.The tumor size (P =0.012)and smoking (P =0.014)had significant difference by χ2 test.The number of tumor (P =0.027),tumor size (P =0.018)and smoking (P <0.001)had significant difference by multivariate analysis. Conclusions The number of tumor,tumor size is an important factor af-fecting the prognosis of patients with bladder cancer.Smoking history might be one of the important factors influence the recurrence of patients with T1 high grade urothelial carcinoma after operative.