CAJ | 학술논문

目的评价准分子激光原位角膜磨镶术(LASIK)治疗近视眼的远期疗效.方法回顾性系列病例研究.选取LASIK术后随访≥5年资料完整者68例(125眼),根据术前等效球镜度分为低中度近视组76眼,等效球镜度-0.75～-6.00(-3.79±1.41)D;高度近视组49眼,等效球镜度-6.12～-13.25(-8.13±1.35)D.术后1个月、6个月、1年、5年检查裸眼视力(UCVA)、最佳矫正视力(BCVA)、裂隙灯、角膜地形图和眼底情况,最后一次复查填写满意程度问卷调查表.对数据进行x2检验、配对样本t检验.结果低中度近视组和高度近视组术后5年裸眼视力≥0.5的比例分别为100％和96％;术后5年等效球镜度在±1.00 D范围的比例分别为93％和84％;术后最后一次复查最佳矫正视力没有变化或增加的占82％眼(103/125);术后5年等效球镜度分别为(-0.02± 0.65)D和(-0.33± 0.80)D,与术后1年比较差异均无统计学意义;l眼术中发生部分游离瓣,1眼术后发生上皮植入,8眼进行了增效手术;两组术后1～5年间均没有出现与手术相关的并发症,患者的满意程度较高.结论 LASIK手术治疗近视术后5年有较好的有效性、安全性和满意度,手术并发症少,术后5年屈光度稳定,远期没有手术相关的并发症发生.
목적 평개준분자격광원위각막마양술(LASIK)치료근시안적원기료효.방법 회고성계렬병례연구.선취LASIK술후수방≥5년자료완정자68례(125안),근거술전등효구경도분위저중도근시조76안,등효구경도-0.75～-6.00(-3.79±1.41)D;고도근시조49안,등효구경도-6.12～-13.25(-8.13±1.35)D.술후1개월、6개월、1년、5년검사라안시력(UCVA)、최가교정시력(BCVA)、렬극등、각막지형도화안저정황,최후일차복사전사만의정도문권조사표.대수거진행x2검험、배대양본t검험.결과 저중도근시조화고도근시조술후5년라안시력≥0.5적비례분별위100％화96％;술후5년등효구경도재±1.00 D범위적비례분별위93％화84％;술후최후일차복사최가교정시력몰유변화혹증가적점82％안(103/125);술후5년등효구경도분별위(-0.02± 0.65)D화(-0.33± 0.80)D,여술후1년비교차이균무통계학의의;l안술중발생부분유리판,1안술후발생상피식입,8안진행료증효수술;량조술후1～5년간균몰유출현여수술상관적병발증,환자적만의정도교고.결론 LASIK수술치료근시술후5년유교호적유효성、안전성화만의도,수술병발증소,술후5년굴광도은정,원기몰유수술상관적병발증발생.
Objective To evaluate long-term refractive outcomes of laser in situ keratomileusis (LASIK) for all levels of myopia.Methods This was a retrospective case series study.One hundred twenty-five eyes of 68 patients who underwent LASIK for myopia and completed over 5 years of follow-up were included in the study.Based on the preoperative spherical equivalent refraction,the eyes were divided into 2 groups.Group A eyes ranged between-0.75 and-6.00 diopters (D) (mild-to-moderate myopia).Group B eyes ranged between-6.12 and-13.25 D (severe myopia).Before and at 1 month,6 months,1 year and 5 years after the operation,uncorrected visual acuity (UCVA),best corrected visual acuity (BCVA),slit-lamp biomicroscopy of the anterior segment,indirect ophthalmoscopy and topography were measured.At the time of the last follow-up,all patients completed a questionnaire assessing their satisfaction with the procedure.Data were analyzed using x2 test and paired t test.Results Uncorrected visual acuity ≥0.5 in groups A and B was obtained in 100％ and 96％ of eyes,and spherical equivalent refraction within ±1.00 D was obtained in 93％ and 84％ of eyes at 5 years.Spherical equivalent refraction in groups A and B was-0.021±0.65 D and-0.33±0.80 D,respectively,at five years.The differences compared with 1-year outcomes after the operation were not statistically significant.BCVA was unchanged or improved in 82％ of all eyes (103/125).Overall,only 1 epithelial ingrowth and l free partial flap were identified as complications from LASIK.Refraction did not regress in either group between 1 and 5 years.Late-onset complications attributable to LASIK were not observed at the 5-year follow-up,and patient satisfaction with the procedure was high.Conclusion A long-term follow-up study of patients after undergoing LASIK for myopia shows it is a safe and effective procedure in correcting all levels of myopia.Complications were rare and patient satisfaction with the surgery was high.Refractive stability was maintained over the 5-year period.Late-onset complications attributable to LASIK were not noted.