CAJ | 학술논문

甲状旁腺素（ PTH）和甲状旁腺素相关肽（ PTHrP）是一类多肽类激素，它们具有相似的基因结构、相同的膜受体，在人体钙、磷代谢过程中起着重要的调节作用。 PTH和PTHrP及其受体除表达于肿瘤组织外，在皮肤、毛囊等正常组织也有表达。它们对表皮增殖分化、毛发生长的生理作用等方面，有望成为银屑病等常见皮肤病的治疗新靶点。
갑상방선소（ PTH）화갑상방선소상관태（ PTHrP）시일류다태류격소，타문구유상사적기인결구、상동적막수체，재인체개、린대사과정중기착중요적조절작용。 PTH화PTHrP급기수체제표체우종류조직외，재피부、모낭등정상조직야유표체。타문대표피증식분화、모발생장적생리작용등방면，유망성위은설병등상견피부병적치료신파점。
Parathyroid hormone/parathyroid hormone-related peptides are polypeptide hormones. They have similar gene struc-ture and same membrane receptor .They play great roles in regulating the calcium and phosphorus metabolism in vivo.PTH/PTHrP and their receptors are expressed in tissues of tumor ,skin, hair follicle and other normal tissues .Because of their physiological action on the proliferation and differentiation of epidermis and hair growth ,they may be a potential therapeutic target for some skin diseases including psoriasis.