磁共振成像
磁共振成像
자공진성상
CHINESE JOURNAL OF MAGNETIC RESONANCE IMAGING
2014年
6期
446-450
,共5页
蒋雯%荆京%梁伟%吕艳伟%程晓光
蔣雯%荊京%樑偉%呂豔偉%程曉光
장문%형경%량위%려염위%정효광
脑白质病,进行性多灶性%磁共振成像%Fazekas量表
腦白質病,進行性多竈性%磁共振成像%Fazekas量錶
뇌백질병,진행성다조성%자공진성상%Fazekas량표
Leukoencephalopathy,progressive multifocal%Magnetic resonance imaging%Fazekas scale
目的:比较北京地区城市和乡村人群的脑白质变性程度的差异。材料与方法选取2012年12月至2014年2月于北京积水潭医院行脑MRI检查的居住于北京市内及乡村的中老年患者,排除DWI证实的及大面积的脑梗死、脑出血、脑积水和其他白质变性疾病,共82例:城市人41例,其中男13例,女28例,年龄56~72岁,平均(62.85±4.28)岁;乡村人41例,其中男17例,女24例,年龄56~69岁,平均(62.68±4.00)岁。使用Fazekas量表对脑白质变性评分。使用两组独立样本的t检验比较城市和乡村人群的年龄差异,χ2检验比较2组性别构成的差异。使用两组独立样本的秩和检验比较2组人群脑白质变性程度的差异,使用秩相关研究年龄与Fazekas量表总分的关系。结果2组人群的年龄(t=0.187, P=0.852,P>0.05)和性别(P=0.395,P>0.05)构成均没有统计学差异,可排除年龄和性别因素对结果的影响。2组人群脑白质变性程度存在明显差异(Z=-2.730, P=0.006,P<0.05),北京地区乡村人群脑白质变性程度(总分的平均秩次为48.15)较城市人群(总分的平均秩次为34.85)严重。年龄与Fazekas量表总分存在相关性(r=0.484,P=0.000,P<0.05),脑白质变性随着年龄的增加而增重。结论北京地区乡村人群的脑白质变性程度较城市人群严重,将来发生认知障碍和脑血管事件的可能性较高,故需要给予乡村人群更多的重视。
目的:比較北京地區城市和鄉村人群的腦白質變性程度的差異。材料與方法選取2012年12月至2014年2月于北京積水潭醫院行腦MRI檢查的居住于北京市內及鄉村的中老年患者,排除DWI證實的及大麵積的腦梗死、腦齣血、腦積水和其他白質變性疾病,共82例:城市人41例,其中男13例,女28例,年齡56~72歲,平均(62.85±4.28)歲;鄉村人41例,其中男17例,女24例,年齡56~69歲,平均(62.68±4.00)歲。使用Fazekas量錶對腦白質變性評分。使用兩組獨立樣本的t檢驗比較城市和鄉村人群的年齡差異,χ2檢驗比較2組性彆構成的差異。使用兩組獨立樣本的秩和檢驗比較2組人群腦白質變性程度的差異,使用秩相關研究年齡與Fazekas量錶總分的關繫。結果2組人群的年齡(t=0.187, P=0.852,P>0.05)和性彆(P=0.395,P>0.05)構成均沒有統計學差異,可排除年齡和性彆因素對結果的影響。2組人群腦白質變性程度存在明顯差異(Z=-2.730, P=0.006,P<0.05),北京地區鄉村人群腦白質變性程度(總分的平均秩次為48.15)較城市人群(總分的平均秩次為34.85)嚴重。年齡與Fazekas量錶總分存在相關性(r=0.484,P=0.000,P<0.05),腦白質變性隨著年齡的增加而增重。結論北京地區鄉村人群的腦白質變性程度較城市人群嚴重,將來髮生認知障礙和腦血管事件的可能性較高,故需要給予鄉村人群更多的重視。
목적:비교북경지구성시화향촌인군적뇌백질변성정도적차이。재료여방법선취2012년12월지2014년2월우북경적수담의원행뇌MRI검사적거주우북경시내급향촌적중노년환자,배제DWI증실적급대면적적뇌경사、뇌출혈、뇌적수화기타백질변성질병,공82례:성시인41례,기중남13례,녀28례,년령56~72세,평균(62.85±4.28)세;향촌인41례,기중남17례,녀24례,년령56~69세,평균(62.68±4.00)세。사용Fazekas량표대뇌백질변성평분。사용량조독립양본적t검험비교성시화향촌인군적년령차이,χ2검험비교2조성별구성적차이。사용량조독립양본적질화검험비교2조인군뇌백질변성정도적차이,사용질상관연구년령여Fazekas량표총분적관계。결과2조인군적년령(t=0.187, P=0.852,P>0.05)화성별(P=0.395,P>0.05)구성균몰유통계학차이,가배제년령화성별인소대결과적영향。2조인군뇌백질변성정도존재명현차이(Z=-2.730, P=0.006,P<0.05),북경지구향촌인군뇌백질변성정도(총분적평균질차위48.15)교성시인군(총분적평균질차위34.85)엄중。년령여Fazekas량표총분존재상관성(r=0.484,P=0.000,P<0.05),뇌백질변성수착년령적증가이증중。결론북경지구향촌인군적뇌백질변성정도교성시인군엄중,장래발생인지장애화뇌혈관사건적가능성교고,고수요급여향촌인군경다적중시。
To evaluate the difference of degree of white matter degeneration between urban and rural population in Beijing.Material and Methods:Except cerebral infarction (diagnosed by DWI), hemorrhage, hydrocephalus and other white matter degeneration diseases, the MR image was obtained in a cohort of 41 urban [aged 56-72 years, mean age (62.85±4.28) years, 13 males and 28 females] and 41 rural patients [aged 56-69 years, mean age (62.68±4.00) years, 17 males and 24 females] who live in Beijing. The Fazekas scale was used to evaluate the degree of white matter degeneration. Independent-samplest test was made to exclude effect of age, andχ2 test was made to exclude the effect of gender. Independent-samples rank sum test was made to evaluate the difference of degree of white matter degeneration between urban and rural population. Rank correlation was made to evaluate the influence of age on total score according to the Fazekas scale.Results:There was statistically signiifcant difference in degree of white matter degeneration between urban and rural population in Beijing (Z=-2.730,P=0.006,P<0.05). And the inlfuence of age (t=0.187,P=0.852,P>0.05) and gender (P=0.395,P>0.05) can be excluded. The degree of white matter degeneration in rural population (mean rank 48.15) was more serious than that in urban population (mean rank 34.85). There was correlation between age and total score (r=0.484,P=0.000,P<0.05). The degree of white matter degeneration increased with age. Conclusions:The degree of white matter degeneration in rural population in Beijing is more severe than that in urban population. Rural population in Beijing may have a greater possibility of cerebral vascular disease and cognitive disorder. Therefore, more attention should be paid to rural population.