CAJ | 학술논문

目的：对梅毒硬下疳患者采用苄星青霉素联合皮肤物理抗菌膜方法治疗的临床效果进行评价。方法46例梅毒硬下疳患者，按照随机分配表的方法分成治疗组与对照组，每组23例。其中对照组仅采用单纯的苄星青霉素的方法治疗，治疗组采用苄星青霉素联合皮肤物理抗菌膜的方法治疗。比较两组患者的愈合率、阳性率及梅毒二期皮疹率。结果治疗组的愈合率明显高于对照组的愈合率；治疗组的阳性率(4.35%)明显低于对照组阳性率(26.09%)；治疗组二期皮疹率(0)明显低于对照组二期皮疹率(21.74%)，差异具有统计学意义(P<0.05)。结论采用苄星青霉素联合皮肤物理抗菌膜方法治疗的临床效果优于单一的苄星青霉素方法治疗，建议广泛使用。
목적：대매독경하감환자채용변성청매소연합피부물리항균막방법치료적림상효과진행평개。방법46례매독경하감환자，안조수궤분배표적방법분성치료조여대조조，매조23례。기중대조조부채용단순적변성청매소적방법치료，치료조채용변성청매소연합피부물리항균막적방법치료。비교량조환자적유합솔、양성솔급매독이기피진솔。결과치료조적유합솔명현고우대조조적유합솔；치료조적양성솔(4.35%)명현저우대조조양성솔(26.09%)；치료조이기피진솔(0)명현저우대조조이기피진솔(21.74%)，차이구유통계학의의(P<0.05)。결론채용변성청매소연합피부물리항균막방법치료적림상효과우우단일적변성청매소방법치료，건의엄범사용。
Objective To evaluate the clinical effect of benzathine benzylpenicillin combined with skin physical antimicrobial membrane in the treatment of chancre syphilitique patients. Methods A total of 46 chancre syphilitique patients were divided into treatment group and control group by random distribution table, with 23 cases in each group. The control group received single benzathine benzylpenicillin treatment, while the treatment group received benzathine benzylpenicillin combined with skin physical antimicrobial membrane. The healing rate, positive rate, and phaseⅡsyphilis rash rate of the two groups were compared. Results The healing rate of the treatment group was significantly higher than that of the control group. The positive rate of the treatment group (4.35%) was obviously lower than that of the control group (26.09%). The phaseⅡsyphilis rash rate in the treatment group (0) was lower than that in the control group (21.74%). The difference had statistical significance (P<0.05). Conclusion The combination of benzathine benzylpenicillin and skin physical antimicrobial membrane has better curative effect than the single treatment by benzathine benzylpenicillin, and this method is worthy of wide application.