CAJ | 학술논문

目的：探讨姑息性化疗对中晚期肺癌患者近期生存率的影响。方法：2009年1月-2012年12月收治中晚期肺癌患者80例，按照治疗方案分为姑息性化疗组和非化疗组，比较两组患者治疗12个月后，生存率、卡诺夫斯基健康状况(KPS)量表评分及肿瘤患者生活质量评分。结果：治疗12个月后，姑息性化疗组患者生存率明显高于非化疗组，患者KPS评分明显高于非化疗组，生活质量评分总分明显高于非化疗组(P＜0.05)。结论：姑息性化疗可有效改善中晚期肺癌患者的生活质量，提高患者近期生存率，值得临床推广应用。
목적：탐토고식성화료대중만기폐암환자근기생존솔적영향。방법：2009년1월-2012년12월수치중만기폐암환자80례，안조치료방안분위고식성화료조화비화료조，비교량조환자치료12개월후，생존솔、잡낙부사기건강상황(KPS)량표평분급종류환자생활질량평분。결과：치료12개월후，고식성화료조환자생존솔명현고우비화료조，환자KPS평분명현고우비화료조，생활질량평분총분명현고우비화료조(P＜0.05)。결론：고식성화료가유효개선중만기폐암환자적생활질량，제고환자근기생존솔，치득림상추엄응용。
Objective:To investigate the influence of palliative chemotherapy on recent survival rate in patients with advanced lung cancer.Methods:80 patients with advanced lung cancer were selected from January 2009 to December 2012.They were divided into the palliative chemotherapy group and the non chemotherapy group according to the treatment plan. The survival rate, the scores of Karnofsky scale(KPS) and scores of life quality in patients with tumor of two groups at 12 months after treatment were compared.Results:12 months after the treatment,the survival rate of the palliative chemotherapy group was significantly higher than that of the non chemotherapy group,furthermore,the scores of KPS and the quality of life score also were significantly higher than that of the non chemotherapy group(P<0.05).Conclusion:Palliative chemotherapy can effectively improve the quality of life in patients with advanced lung cancer,and also can improve the survival rate of patients,so it is worthy of clinical application.