中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
32期
120-120,122
,共2页
扩张型心肌病%脑钠肽%预后
擴張型心肌病%腦鈉肽%預後
확장형심기병%뇌납태%예후
Dilated cardiomyopathy%Brain natriuretic peptide%Prognosis
目的：评估 NT-proBNP 对扩张型心肌病(DCM)心衰患者的预后价值。方法：对78例 DCM 患者检测NT-proBNP 和射血分数(LVEF)，随访中位数13.5个月(3～25个月)，观察心血管事件(心源性死亡及心衰失代偿再入院)情况。结果：①再发事件组 LVEF 更低[(39.4±8.2)% vs(46.2±8.6)%]，NT-proBNP 中位数更高(6803.0 pg/mL vs 2464.0 pg/mL)， P＜0.01，肌酐较高[(113.6±48.4)μ mol/L vs(90.6±31.1)μ mol/L]， P＜0.05。② Cox 模型显示lg(NT-proBNP)是 DCM 患者独立的心血管事件再发生的预后因素，OR=3.775(95%CI 1.668～8.540，P=0.001)。结论：NT-proBNP对DCM患者预后评估有重要价值。
目的：評估 NT-proBNP 對擴張型心肌病(DCM)心衰患者的預後價值。方法：對78例 DCM 患者檢測NT-proBNP 和射血分數(LVEF)，隨訪中位數13.5箇月(3～25箇月)，觀察心血管事件(心源性死亡及心衰失代償再入院)情況。結果：①再髮事件組 LVEF 更低[(39.4±8.2)% vs(46.2±8.6)%]，NT-proBNP 中位數更高(6803.0 pg/mL vs 2464.0 pg/mL)， P＜0.01，肌酐較高[(113.6±48.4)μ mol/L vs(90.6±31.1)μ mol/L]， P＜0.05。② Cox 模型顯示lg(NT-proBNP)是 DCM 患者獨立的心血管事件再髮生的預後因素，OR=3.775(95%CI 1.668～8.540，P=0.001)。結論：NT-proBNP對DCM患者預後評估有重要價值。
목적：평고 NT-proBNP 대확장형심기병(DCM)심쇠환자적예후개치。방법：대78례 DCM 환자검측NT-proBNP 화사혈분수(LVEF)，수방중위수13.5개월(3～25개월)，관찰심혈관사건(심원성사망급심쇠실대상재입원)정황。결과：①재발사건조 LVEF 경저[(39.4±8.2)% vs(46.2±8.6)%]，NT-proBNP 중위수경고(6803.0 pg/mL vs 2464.0 pg/mL)， P＜0.01，기항교고[(113.6±48.4)μ mol/L vs(90.6±31.1)μ mol/L]， P＜0.05。② Cox 모형현시lg(NT-proBNP)시 DCM 환자독립적심혈관사건재발생적예후인소，OR=3.775(95%CI 1.668～8.540，P=0.001)。결론：NT-proBNP대DCM환자예후평고유중요개치。
Objective:To evaluate NT-proBNP in patients with dilated cardiomyopathy(DCM)patients with heart failure value. Methods:78 patients with DCM were detected the NT-proBNP and ejection fraction(LVEF).The median follow-up was 13.5 months(3~25 months).We observed the cardiovascular events(cardiac death and heart failure decompensation readmission) situation.Results:①The recurrent event group had lower LVEF[(39.4±8.2)% vs(46.2±8.6)%];NT-proBNP median was higher(6 803.0 pg/mL vs 2 464.0 pg/mL),P<0.01;creatinine was higher[(113.6±48.4)μmol/L vs(90.6±31.1)μmol/L],P<0.05.②Cox model showed lg (NT-proBNP) was an independent prognostic factor in patients with DCM recurrence of cardiovascular events, OR=3.775(95%CI:1.668~8.540,P=0.001).Conclusion:NT-proBNP for prognosis in patients with DCM has an important value.
