CAJ | 학술논문

目的：探讨早期乳腺癌保乳手术中肿块切除的安全瘤缘距离。方法收集两家医院近年行肿块局部扩大切除术的84例早期乳腺癌保乳手术患者的临床资料及5年随诊资料，对切除肿块瘤缘距离为1cm的44例患者（A组）与2cm的40例患者（B组）的资料进行比较，对照分析两组患者的手术情况和预后。结果两组的手术时间、术中出血量及并发症发生率的差异均无统计学意义（均P＞0.05），A组第1次切缘阳性患者的占比、局部复发及远处转移率均较B组为高，但两组的差异也均无统计学意义（均P＞0.05）。结论为增加保乳手术的成功率，术中肿块切除的安全瘤缘距离应以2cm为宜。
목적：탐토조기유선암보유수술중종괴절제적안전류연거리。방법수집량가의원근년행종괴국부확대절제술적84례조기유선암보유수술환자적림상자료급5년수진자료，대절제종괴류연거리위1cm적44례환자（A조）여2cm적40례환자（B조）적자료진행비교，대조분석량조환자적수술정황화예후。결과량조적수술시간、술중출혈량급병발증발생솔적차이균무통계학의의（균P＞0.05），A조제1차절연양성환자적점비、국부복발급원처전이솔균교B조위고，단량조적차이야균무통계학의의（균P＞0.05）。결론위증가보유수술적성공솔，술중종괴절제적안전류연거리응이2cm위의。
Objective To evaluate the safety distance of lumpectomy margin in breast- conserving surgery for early breast cancer Methods Clinical data of 84 patients with early breast cancer, who underwent breast- conserving surgery and were fol owed- up for 5 years, were retrospectively analyzed. There were 44 patients (group A) with the resection margin of 1 cm from the tumor edge and 40 patients (group B) with the resection margin of 2 cm. The correlation between surgical treatment and prognosis was analyzed in two groups. Results There were no significant differences in operation time, intraoperative blood loss and complication rate between two groups (P>0.05). The rates of positive margin, local recurrence and distant metastasis in group A seemed to be higher than those in group B, but there were not significant differences between groups (P>0.05). Conclusion To increase the success rate of breast- conserving surgery, the safe resection margin of 2cm from the tumor edge seems to be safer.