CAJ | 학술논문

目的：建立人血中Pb、Cd、Hg、Mn、Cu、Co、V、Ni、Mo、Zn、Tl、Ag、Sb、Ti等14种金属和Sc、Ce、Pr、Nd、Sm、Eu、Gd、Tb、Dy等15种稀土元素检测的新方法。方法血样经硝酸水浴消解后，经电感耦合等离子体质谱法直接同时测定血中的多种金属元素。结果29种元素的检出限在0.03～0.46μg/L之间，RSD均小于4.2%，质控样品SeronormTM Trace Elements whole Blood L-2中29种元素测定的结果均在标准值参考范围内。结论该方法简单，检出限低，精密度度好，准确度高，适用于人血中的重金属元素及稀土元素的检测。
목적：건립인혈중Pb、Cd、Hg、Mn、Cu、Co、V、Ni、Mo、Zn、Tl、Ag、Sb、Ti등14충금속화Sc、Ce、Pr、Nd、Sm、Eu、Gd、Tb、Dy등15충희토원소검측적신방법。방법혈양경초산수욕소해후，경전감우합등리자체질보법직접동시측정혈중적다충금속원소。결과29충원소적검출한재0.03～0.46μg/L지간，RSD균소우4.2%，질공양품SeronormTM Trace Elements whole Blood L-2중29충원소측정적결과균재표준치삼고범위내。결론해방법간단，검출한저，정밀도도호，준학도고，괄용우인혈중적중금속원소급희토원소적검측。
Objective To establish the method for the determination of 29 elements in blood by Inductively Coupled Plasma Mass Spectrometry (ICP-MS).Methods The samples were digested by HNO3 dissolution system in water bath. The solution was directly analyzed by ICP-MS for the determination of 29 elements.Results The detection limits of each elementwas between 0.03 μg /L ~0.46 μg /L. Relative standard deviations were below 4.2%. Standard reference materials were used quality control standards and the analysis results conformed well to the certified values.Conclusion The method was proved to be simple,rapid,accurate and reliable. And it has been applied to the determination of metal elements in blood with satisfactory results.