海南医学
海南醫學
해남의학
HAINAN MEDICAL JOURNAL
2014年
21期
3186-3187,3188
,共3页
筛查%意外抗体%“Mur”抗原%抗“Mur”抗体
篩查%意外抗體%“Mur”抗原%抗“Mur”抗體
사사%의외항체%“Mur”항원%항“Mur”항체
Screening%Unexpected antibody%Mur antigen%anti-Mur antibody
目的:通过对“Mur”抗原的制备研究,探讨意外抗体筛查检出抗“Mur”抗体的临床意义,为临床选择合适的血液,预防输血反应,确保有效输血及输血安全。方法首先用含Mur抗原谱细胞筛查出抗“Mur”抗体,然后用该抗“Mur”抗体制备“Mur”抗原作为4号筛查细胞,用于输血前的意外抗体筛查。结果8200例抗体筛查中抗“Mur”抗体阳性68例,阳性率为0.83%。该68例患者中,33例有反复输血史,26例有妊娠史,由于产生意外抗体而引起疑难配血者38例。结论意外抗体筛查检出抗“Mur”抗体能有效提高临床输血安全,具有重要的临床价值。
目的:通過對“Mur”抗原的製備研究,探討意外抗體篩查檢齣抗“Mur”抗體的臨床意義,為臨床選擇閤適的血液,預防輸血反應,確保有效輸血及輸血安全。方法首先用含Mur抗原譜細胞篩查齣抗“Mur”抗體,然後用該抗“Mur”抗體製備“Mur”抗原作為4號篩查細胞,用于輸血前的意外抗體篩查。結果8200例抗體篩查中抗“Mur”抗體暘性68例,暘性率為0.83%。該68例患者中,33例有反複輸血史,26例有妊娠史,由于產生意外抗體而引起疑難配血者38例。結論意外抗體篩查檢齣抗“Mur”抗體能有效提高臨床輸血安全,具有重要的臨床價值。
목적:통과대“Mur”항원적제비연구,탐토의외항체사사검출항“Mur”항체적림상의의,위림상선택합괄적혈액,예방수혈반응,학보유효수혈급수혈안전。방법수선용함Mur항원보세포사사출항“Mur”항체,연후용해항“Mur”항체제비“Mur”항원작위4호사사세포,용우수혈전적의외항체사사。결과8200례항체사사중항“Mur”항체양성68례,양성솔위0.83%。해68례환자중,33례유반복수혈사,26례유임신사,유우산생의외항체이인기의난배혈자38례。결론의외항체사사검출항“Mur”항체능유효제고림상수혈안전,구유중요적림상개치。
Objective To investigate the clinical significance of unexpected antibody screening with detec-tion of anti-Mur antibody by preparation of Mur antigen, for the purpose of selecting the appropriate blood for clini-cal transfusion, preventing the transfusion reaction and assuring the safety and efficiency in clinical transfusion. Methods First, with panel cells containing Mur antigen, we screened out anti-Mur antibody. Then, we prepared the Mur antigen as new sieve cells used in unexpected blood screening before transfusion. Results Totally 68 (0.83%) samples were positive among 8 200 samples by antibody screen test. Of the 68 cases, 33 cases had a history of repeat-ed transfusion, 26 cases had a history of pregnancy and 38 cases had difficulty of blood matching because of the unex-pected antibody. Conclusion Screening of unexpected antibody (anti-Mur) could effectively improve the safety of clini-cal transfusion, which is of great clinical value.