CAJ | 학술논문

目的：评价蛛网膜下腔出血（SAH）后脑血管痉孪（CVS）患者应用尼莫地平防治的临床效果。方法选择我院2012-04-2014-01收治的73例蛛网膜下腔出血患者，根据治疗药物的不同随机分为观察组（37例）与对照组（36例），对照组采用常规治疗方法如脱水、降颅压及止血等，观察组在对照组基础上加用尼莫地平。结果观察组经治疗后总有效率为94.59％，明显好于对照组的72.22％，差异有统计学意义（ P＜0.05）。观察组脑血管痉挛的发生率、再出血率及病死率均明显低于对照组，差异有统计学意义（ P＜0.05）。结论尼莫地平在预防和治疗蛛网膜下腔出血后脑血管出现痉挛方面疗效显著，较好地减少脑血管痉挛的发生率、再出血率及病死率。
목적：평개주망막하강출혈（SAH）후뇌혈관경련（CVS）환자응용니막지평방치적림상효과。방법선택아원2012-04-2014-01수치적73례주망막하강출혈환자，근거치료약물적불동수궤분위관찰조（37례）여대조조（36례），대조조채용상규치료방법여탈수、강로압급지혈등，관찰조재대조조기출상가용니막지평。결과관찰조경치료후총유효솔위94.59％，명현호우대조조적72.22％，차이유통계학의의（ P＜0.05）。관찰조뇌혈관경련적발생솔、재출혈솔급병사솔균명현저우대조조，차이유통계학의의（ P＜0.05）。결론니막지평재예방화치료주망막하강출혈후뇌혈관출현경련방면료효현저，교호지감소뇌혈관경련적발생솔、재출혈솔급병사솔。
Objective To evaluate the clinical efficacy of Nimodipine on prevention of subarachnoid hemorrhage of patients with cerebral vasospasm.Methods In our hospital from April 2012 to January 2014 were treated 73 patients with subarachnoid hemorrhage ,according to the different treatments were randomly divided into observation group (37 cases) and control group (36 cases) ,control group patients with dehydration ,reduced conventional treatments such as intracranial pressure and bleeding was observed in this group with Nimodipine therapy plus basis.Results The patients were treated after the total effective rate was 94.59% ,significantly better than 72.22% of the control group ,the difference was statistically significant effect (P<0.05). The incidence of cerebral vascular spasm of patients in the observation group ,rebleeding and mortality rates were sig-nificantly lower than those the control group ,the difference was statistically significant (P<0.05).Conclusion Nimodipine in the prevention and treatment of subarachnoid hemorrhage of blood vessels spasm side effect is significant ,in order to reduce the incidence of cerebrovascular spasm of rebleeding and mortality.